Evidence map›Paper›PMID 29907754›Full record

ArticleScientific reports2018

Nano-particle mediated inhibition of Parkinson's disease using computational biology approach.

Aman Chandra Kaushik, Shiv Bharadwaj, Sanjay Kumar, Dong-Qing Wei

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Periodic Table of Immunomodulatory Elements and Derived Two-Dimensional Biomaterials.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Interaction of silver nanoparticles with catecholBiochemistry and biophysics reports · 2021
    Article
  9. Physiological and Pathological Factors Affecting Drug Delivery to the Brain by Nanoparticles.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
  10. Personalized Healthcare for Dementia.Healthcare (Basel, Switzerland) · 2021
    Review
  11. Emerging Nanotechnology for Treatment of Alzheimer's and Parkinson's Disease.Frontiers in bioengineering and biotechnology · 2021
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aman Chandra KaushikState Key Laboratory of Microbial Metabolism and School of life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.
Shiv BharadwajSabanci University Nanotechnology Research and Application Center, Orta Mah. Tuzla, 34956, Istanbul, Turkey.
Sanjay KumarBioinformatics Centre, Biotech Park, Lucknow, 226018, India.
Dong-Qing WeiState Key Laboratory of Microbial Metabolism and School of life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China. dqwei@sjtu.edu.cn.ORCID 0000-0003-4200-7502

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease (PD) arises as neurodegenerative disorder and characterized by progressive deterioration of motor functions due to forfeiture of dopamine-releasing neurons. During PD, neurons at stake loss their functionality that results into cognition impairment and forgetfulness, commonly called as dementia. Recently, nanoparticles (NPs) have been reported for easy drug delivery through blood-brain barrier (BBB) into the central nervous system (CNS) against the conventional drug delivery systems. However, present study attempted to elucidate the α-synuclein activity, a major factor casing PD, in presence of its inhibitor cerium oxide (CeO

Indexed as

alpha-SynucleinMolecular Dynamics SimulationBlood-Brain BarrierCeriumHumansNanoparticlesParkinson Diseasealpha-Synucleinceric oxideCeriumSNCA protein, human

Identifiers

PMID29907754
PMCPMC6003935

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.