ArticleNature communications2018
Single-breath-hold photoacoustic computed tomography of the breast.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07784179 (Ultrasound and Photoacoustic Imaging of Hydrocephalus), which is not on this map. Cited by 238 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ultrasound and Photoacoustic Imaging of Hydrocephalus
Who cites it
238 citing papers in PubMed, 1 synthesis or guideline pooled it, 449 citations in OpenAlex.
- Noninvasive hemoglobin sensing and imaging: optical tools for disease diagnosis.Journal of biomedical optics · 2022Pooled it
- Benchmarking deep learning-based reconstruction methods for photoacoustic computed tomography with clinically relevant synthetic datasets.Journal of biomedical optics · 2027Article
- Photoacoustic and ultrasound Imaging of placental functions in gestational diabetes: From diagnosis to precision interventions.Photoacoustics · 2026Review
- Advanced methods of wearable ultrasound and photoacoustic imaging devices: A review.Photoacoustics · 2026Article
- A virtual imaging framework for three-dimensional quantitative optoacoustic tomography using stochastic numerical breast phantoms.Photoacoustics · 2026Article
- Two-Photon Endomicroscopy for Image-Guided Magnetic Micro-Agents.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Deep Learning for scaling large-aperture photoacoustic computed tomography : From single fingers to the human hand.Ultrasonics · 2026Article
- Hybrid three-dimensional full-view multi-wavelength photoacoustic and ultrasound breast tomography.Photoacoustics · 2026Article
- Multiple reflection: A Route to enhanced sensitivity in beam-deflection optical ultrasound sensing.Photoacoustics · 2026Article
- Mapping the research landscape of photoacoustic imaging in breast cancer: a text-based bibliometric analysis.Gland surgery · 2026Article
- High-Speed Volumetric Dual-Mode Ultrasound and Photoacoustic Tomography With a Single-Element Detector.IEEE transactions on medical imaging · 2026Article
- Whole cross-sectional human ultrasound tomography.Nature biomedical engineering · 2026Article
- Photoacoustic Imaging for Women's Gynecological Health: Advances and Clinical Prospects.Bioengineering (Basel, Switzerland) · 2026Review
- Utilizing post-imaging surveys to guide development of photoacoustic computed technology for breast imaging.American journal of surgery · 2026Article
- Volumetric photoacoustic/ultrasound image fusion and enhancement with dual-tree complex wavelet transform.Biomedical optics express · 2026Article
- Impact of skin pigmentation on photoacoustic tomography: a phantom study.Biophotonics discovery · 2026Article
- Photoacoustic imaging: An emerging tool for intraoperative margin assessment in breast-conserving surgery.Photoacoustics · 2026Review
- Curvy Surface Reconstruction.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Rotational ultrasound and photoacoustic tomography of the human body.Nature biomedical engineering · 2026Article
- Vascular Phenotyping with Photoacoustic and Ultrasound Imaging in Cardiovascular Disease: Recent Innovations.Current treatment options in cardiovascular medicine · 2026Review
178 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
We have developed a single-breath-hold photoacoustic computed tomography (SBH-PACT) system to reveal detailed angiographic structures in human breasts. SBH-PACT features a deep penetration depth (4 cm in vivo) with high spatial and temporal resolutions (255 µm in-plane resolution and a 10 Hz 2D frame rate). By scanning the entire breast within a single breath hold (~15 s), a volumetric image can be acquired and subsequently reconstructed utilizing 3D back-projection with negligible breathing-induced motion artifacts. SBH-PACT clearly reveals tumors by observing higher blood vessel densities associated with tumors at high spatial resolution, showing early promise for high sensitivity in radiographically dense breasts. In addition to blood vessel imaging, the high imaging speed enables dynamic studies, such as photoacoustic elastography, which identifies tumors by showing less compliance. We imaged breast cancer patients with breast sizes ranging from B cup to DD cup, and skin pigmentations ranging from light to dark. SBH-PACT identified all the tumors without resorting to ionizing radiation or exogenous contrast, posing no health risks.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.