Evidence map›Paper›PMID 29907648›Full record

ArticleGenetics2018

The Spectrum of Replication Errors in the Absence of Error Correction Assayed Across the Whole Genome of

Brittany A Niccum, Heewook Lee, Wazim MohammedIsmail, Haixu Tang, Patricia L Foster

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 34 citations in OpenAlex.

  1. Extended sequence context shapes mutational bias inProceedings of the National Academy of Sciences of the United States of America · 2026
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  10. Manufacturing DNA inMolecular therapy. Methods & clinical development · 2024
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  13. Antibiotic perseverance increases the risk of resistance development.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
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  15. Review
  16. Article
  17. Article
  18. Alleviation of C⋅C Mismatches in DNA by theFrontiers in microbiology · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Brittany A NiccumDepartment of Biology, Indiana University, Bloomington, Indiana 47405.
Heewook LeeSchool of Informatics, Computing, and Engineering, Indiana University, Bloomington, Indiana 47405.ORCID 0000-0002-3528-6833
Wazim MohammedIsmailSchool of Informatics, Computing, and Engineering, Indiana University, Bloomington, Indiana 47405.
Haixu TangSchool of Informatics, Computing, and Engineering, Indiana University, Bloomington, Indiana 47405.ORCID 0000-0001-8963-8155
Patricia L FosterDepartment of Biology, Indiana University, Bloomington, Indiana 47405 plfoster@indiana.edu.ORCID 0000-0002-7236-4378
Indiana University Bloomington · US

Funding

TRAINING IN GENETICST32GM007757 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI KUMAR, JUSTIN P · 1985 to 2014
$8.1M
NIGMS NIH HHS T32 GM007757
6 · The paper itself

Abstract

When the DNA polymerase that replicates the

Indexed as

DNA ReplicationDNA, BacterialDNA DamageDNA Mismatch RepairDNA Polymerase IIIEscherichia coliEscherichia coli ProteinsMutation RateSOS Response, GeneticsWhole Genome SequencingDNA, BacterialDNA Polymerase IIIEscherichia coli ProteinsDNA proofreadingDNA replication fidelitymismatch repairmutation accumulationmutation hotspots

Identifiers

PMID29907648
PMCPMC6063229
OpenAlexW2807921644

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.