ArticleBMC nephrology2018
A case of immunotactoid glomerulopathy with false-negative IgG staining.
Article in BMC nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 4 citations in OpenAlex.
- Monoclonal immunotactoid glomerulopathy with masked IgG associated with symptomatic multiple myeloma: a case report diagnosed by paraffin-immunofluorescence and mass spectrometry.CEN case reports · 2026Article
- Article
- Diagnosis of monoclonal immunotactoid glomerulopathy with positive λ chain by immunoelectron microscopy.CEN case reports · 2023Article
- Polyclonal Immunotactoid Glomerulopathy Associated with Monoclonal Gammopathy of IgM Type and Underlying Plasmacellular Disease: Successful Treatment with Rituximab Alone.Case reports in nephrology and dialysisArticle
- Immunotactoid Glomerulopathy: A Rare Glomerular Disease Case Study.Indian journal of nephrologyArticle
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundImmunotactoid glomerulopathy (ITG) is a rare glomerulonephritis characterized by microtubular deposits. Immunofluorescence findings are necessary to differentiate ITG from other proliferative glomerular diseases. The characteristic tubular structure on electron microscopy is essential for a definitive diagnosis, and the diameter of the structure has been traditionally used for differentiating between ITG and other types of glomerulonephritis with organized deposits. In recent years, the disease concept of monoclonal gammopathy of renal significance, which is associated with M protein produced by plasma cell tumors, has been proposed. CASE PRESENTATION: This was a peculiar case of ITG with underlying monoclonal gammopathy in which IgG showed a false-negative result with immunofluorescence using frozen sections. Additional examinations using a different clone of the anti-IgG antibody revealed typical IgG staining. C4d was strongly positive, consistent with immune complex type glomerulonephritis.
conclusionsThis case highlights unusual features of ITG, and provides a practical hint to avoid a diagnostic pitfall.
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