Evidence map›Paper›PMID 29906335›Full record

ArticleJournal of diabetes investigation2019

Alpha the versatile: Guardians of the islets.

Dan Kawamori

Abstract read
In one paragraph

Article in Journal of diabetes investigation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Dan KawamoriDepartment of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.ORCID http://orcid.org/0000-0002-0149-8213

Funding

Japan Diabetes FoundationMinistry of Education, Culture, Sports, Science and Technology of Japan
6 · The paper itself

Abstract

Recent progress in α-cell research has newly revealed its versatility including secretion of multiple hormones, trans-differentiation, and abundant proliferation. A recent report from the Kushner laboratory further provided direct evidence of active proliferation of α-cells in both T1D and non-diabetic control donors. α-cells are suggested to maintain both quality and quantity of islets by serving as 'guardians' of the islets.

Indexed as

AnimalsCell ProliferationEnergy MetabolismGlucagon-Secreting CellsHumansInsulinIslets of LangerhansInsulin

Identifiers

PMID29906335
PMCPMC6319495

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.