Evidence map›Paper›PMID 29905935›Full record

ArticleCancer2018

Symptoms of posttraumatic stress disorder among hospitalized patients with cancer.

Ryan D Nipp, Areej El-Jawahri, Sara M D'Arpino, Andy Chan, Charn-Xin Fuh, P Connor Johnson, Daniel E Lage, Risa L Wong, William F Pirl, Lara Traeger and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
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  6. Review
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  13. Associations of patient-reported care satisfaction with symptom burden and healthcare use in hospitalized patients with cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  14. Article
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  19. Healthcare Utilization and End-of-Life Outcomes in Patients Receiving CAR T-Cell Therapy.Journal of the National Comprehensive Cancer Network : JNCCN · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Ryan D NippDivision of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, Massachusetts.ORCID 0000-0002-4577-3248
Areej El-JawahriDivision of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, Massachusetts.ORCID 0000-0002-3556-1495
Sara M D'ArpinoDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Andy ChanDivision of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, Massachusetts.
Charn-Xin FuhDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
P Connor JohnsonDivision of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, Massachusetts.
Daniel E LageDivision of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, Massachusetts.
Risa L WongDivision of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, Massachusetts.ORCID 0000-0003-1658-9465
William F PirlDepartment of Psychiatry, Sylvester Comprehensive Cancer Center and University of Miami, Miami, Florida.
Lara TraegerDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Barbara J CashavellyDivision of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, Massachusetts.
Vicki A JacksonDivision of Palliative Care, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
David P RyanDivision of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, Massachusetts.
Ephraim P HochbergDivision of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, Massachusetts.
Jennifer S TemelDivision of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, Massachusetts.
Joseph A GreerDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Harvard University · USUniversity of Miami · US

Funding

Optimizing Palliative and End of Life Care for Patients with CancerK24CA181253 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI TEMEL, JENNIFER SUE · 2014 to 2018
$737k
NCI NIH HHS K24 CA181253
6 · The paper itself

Abstract

backgroundPatients with cancer experience many stressors placing them at risk for posttraumatic stress disorder (PTSD) symptoms, yet little is known about factors associated with PTSD symptoms in this population. This study explored relationships among patients' PTSD symptoms, physical and psychological symptom burden, and risk for hospital readmissions.

methodsWe prospectively enrolled patients with cancer admitted for an unplanned hospitalization from August 2015-April 2017. Upon admission, we assessed patients' PTSD symptoms (Primary Care PTSD Screen), as well as physical (Edmonton Symptom Assessment System [ESAS]) and psychological (Patient Health Questionnaire 4 [PHQ-4]) symptoms. We examined associations between PTSD symptoms and patients' physical and psychological symptom burden using linear regression. We evaluated relationships between PTSD symptoms and unplanned hospital readmissions within 90-days using Cox regression.

resultsWe enrolled 954 of 1,087 (87.8%) patients approached, and 127 (13.3%) screened positive for PTSD symptoms. The 90-day hospital readmission rate was 38.9%. Younger age, female sex, greater comorbidities, and genitourinary cancer type were associated with higher PTSD scores. Patients' PTSD symptoms were associated with physical symptoms (ESAS physical: B = 3.41; P < .001), the total symptom burden (ESAS total: B = 5.97; P < .001), depression (PHQ-4 depression: B = 0.67; P < .001), and anxiety symptoms (PHQ-4 anxiety: B = 0.71; P < .001). Patients' PTSD symptoms were associated with a lower risk of hospital readmissions (hazard ratio, 0.81; P = .001).

conclusionsA high proportion of hospitalized patients with cancer experience PTSD symptoms, which are associated with a greater physical and psychological symptom burden and a lower risk of hospital readmissions. Interventions to address patients' PTSD symptoms are needed and should account for their physical and psychological symptom burden. Cancer 2018. © 2018 American Cancer Society.

Indexed as

AgedCost of IllnessFemaleHospitalizationHumansMaleMassachusettsMiddle AgedNeoplasmsPatient Acceptance of Health CarePsychological TestsStress Disorders, Post-TraumaticSurveys and Questionnairescancerhospital readmissionsmoodoutcomes researchposttraumatic stress disordersymptoms

Identifiers

PMID29905935
PMCPMC6108928
OpenAlexW2808520028

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.