Evidence map›Paper›PMID 29905532›Full record

ArticleAging2018

Chronic vitamin D insufficiency impairs physical performance in C57BL/6J mice.

Kenneth L Seldeen, Manhui Pang, Merced M Leiker, Jonathan E Bard, Maria Rodríguez-Gonzalez, Mireya Hernandez, Zachary Sheridan, Norma Nowak, Bruce R Troen

Open access · greenAbstract read
In one paragraph

Article in Aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Association Between Vitamin D Supplementation and Statin-Associated Muscle Symptoms: A Systematic Review.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2022
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Pinpointing a Role for Vitamin D in Frailty: A Time for Animal Models?Advances in geriatric medicine and research · 2021
    Article
  10. Nutrition and microRNAs: Novel Insights to Fight Sarcopenia.Antioxidants (Basel, Switzerland) · 2020
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Kenneth L SeldeenDivision of Geriatrics and Palliative Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo and Research Service, Veterans Affairs Western New York Healthcare System, Buffalo, NY 14203, USA.
Manhui PangDivision of Geriatrics and Palliative Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo and Research Service, Veterans Affairs Western New York Healthcare System, Buffalo, NY 14203, USA.
Merced M LeikerDivision of Geriatrics and Palliative Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo and Research Service, Veterans Affairs Western New York Healthcare System, Buffalo, NY 14203, USA.
Jonathan E BardNew York State Center of Excellence in Bioinformatics and Life Sciences and Department of Biochemistry, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14214, USA.
Maria Rodríguez-GonzalezDivision of Geriatrics and Palliative Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo and Research Service, Veterans Affairs Western New York Healthcare System, Buffalo, NY 14203, USA.
Mireya HernandezDivision of Geriatrics and Palliative Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo and Research Service, Veterans Affairs Western New York Healthcare System, Buffalo, NY 14203, USA.
Zachary SheridanDivision of Geriatrics and Palliative Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo and Research Service, Veterans Affairs Western New York Healthcare System, Buffalo, NY 14203, USA.
Norma NowakNew York State Center of Excellence in Bioinformatics and Life Sciences and Department of Biochemistry, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14214, USA.
Bruce R TroenDivision of Geriatrics and Palliative Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo and Research Service, Veterans Affairs Western New York Healthcare System, Buffalo, NY 14203, USA.
VA Western New York Healthcare System · US

Funding

Physical performance in an animal model of vitamin D insufficiencyI21RX001066 · VA · MIAMI VA HEALTH CARE SYSTEM · PI TROEN, BRUCE R. · 2015 to 2015
–
RRD VA I21 RX001066
6 · The paper itself

Abstract

Vitamin D insufficiency (serum 25-OH vitamin D < 30 ng/ml) affects 70-80% of the general population, yet the long-term impacts on physical performance and the progression of sarcopenia are poorly understood. We therefore followed 6-month-old male C57BL/6J mice (

Indexed as

AnimalsBody CompositionBone DensityBone Density Conservation AgentsCytokinesGene Expression RegulationInflammationMaleMiceMice, Inbred C57BLMuscle ProteinsMuscle StrengthSKP Cullin F-Box Protein LigasesVitamin DVitamin D DeficiencyVitaminsBone Density Conservation AgentsCytokinesFbxo32 protein, mouseMuscle ProteinsSKP Cullin F-Box Protein LigasesVitamin DVitaminsmicroRNAmitochondriamusclesarcopeniavitamin D

Identifiers

PMID29905532
PMCPMC6046224
OpenAlexW2808062385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.