ArticleeLife2018
PACAP neurons in the ventral premammillary nucleus regulate reproductive function in the female mouse.
Open access · goldAbstract read
In one paragraph
Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
5.0field-weighted citation impact, top 3% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
51 citing papers in PubMed, 96 citations in OpenAlex.
- Hypothalamic control of puberty: from neuronal circuits to mechanisms for its metabolic regulation.Reviews in endocrine & metabolic disorders · 2026Review
- The ventral hippocampus to paraventricular thalamus circuit regulates context-dependent hyperlocomotion through PAC1 receptor signaling in the chronic stress-induced PTSD mouse model.Translational psychiatry · 2026Article
- Article
- Neuroendocrine plasticity and crosstalk in pubertal development.Journal of neuroendocrinology · 2026Review
- PAC1 Receptor Knockout Mice Reveal Critical Links Between ER Stress, Myelin Homeostasis, and Neurodegeneration.International journal of molecular sciences · 2025Article
- Nutritionally Responsive PMv DAT Neurons Are Dynamically Regulated During Pubertal Transition.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Article
- Brain circuits that regulate social behavior.Molecular psychiatry · 2025Review
- Nutritionally responsive PMv DAT neurons are dynamically regulated during pubertal transition.bioRxiv : the preprint server for biology · 2025Article
- The ventral premammillary nucleus at the interface of environmental cues and social behaviors.Frontiers in neuroscience · 2025Review
- The hypothalamic effects of PACAP on the hypothalamic-pituitary-gonadal axis in male mice.Frontiers in endocrinology · 2025Article
- Spatial Single-Cell Mapping of Transcriptional Differences Across Genetic Backgrounds in Mouse Brains.bioRxiv : the preprint server for biology · 2024Article
- Single nucleus/cell RNA-seq of the chicken hypothalamic-pituitary-ovarian axis offers new insights into the molecular regulatory mechanisms of ovarian development.Zoological research · 2024Article
- Contributions of white adipose tissue to energy requirements for female reproduction.Trends in endocrinology and metabolism: TEM · 2024Review
- Article
- Metabolic control of puberty: 60 years in the footsteps of Kennedy and Mitra's seminal work.Nature reviews. Endocrinology · 2024Review
- Article
- Hypothalamic control of innate social behaviors.Science (New York, N.Y.) · 2023Review
- Genomic Scan for Runs of Homozygosity and Selective Signature Analysis to Identify Candidate Genes in Large White Pigs.International journal of molecular sciences · 2023Article
- Leptin, but not Estradiol, Signaling in PACAP Neurons Modulates Puberty Onset.Endocrinology · 2023Article
- Neural control of female sexual behaviors.Hormones and behavior · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 4 institutions in 2 countries.
Rachel A RossDepartment of Psychiatry, Beth Israel Deaconess Medical Center, Boston, United States.
Silvia LeonHarvard Medical School, Massachusetts, United States.
Joseph C MadaraHarvard Medical School, Massachusetts, United States.
Danielle SchaferCentre for Neuroendocrinology, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand.
Chrysanthi FerganiHarvard Medical School, Massachusetts, United States.
Caroline A MaguireDepartment of Medicine, Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Boston, United States.
Anne Mj VerstegenHarvard Medical School, Massachusetts, United States.
Emily BrengleDepartment of Medicine, Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Boston, United States.
Dong KongDepartment of Neuroscience, Tufts University School of Medicine, Massachusetts, United States.
Allan E HerbisonCentre for Neuroendocrinology, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand.ORCID http://orcid.org/0000-0002-9615-3022
Ursula B KaiserHarvard Medical School, Massachusetts, United States.
Bradford B LowellHarvard Medical School, Massachusetts, United States.
Victor M NavarroHarvard Medical School, Massachusetts, United States.ORCID http://orcid.org/0000-0002-5799-219X
Brigham and Women's Hospital · USBeth Israel Deaconess Medical Center · USUniversity of Otago · NZTufts University · US
Funding
Harvard Clinical and Translational Science CenterUL1TR001102 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$106.2MTransgenic CoreP30DK057521 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI KAHN, BARBARA B. · 2000 to 2019
$31.4MTransgenic CoreP30DK046200 · NIDDK · TUFTS MEDICAL CENTER · PI CORKEY, BARBARA E. · 1992 to 2021
$25.0MHarvard Clinical and Translational Science CenterKL2TR001100 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$8.5MThe routing of hunger/satiety information by the parabrachial nucleus (PBN)R01DK075632 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BRADFORD B LOWELL · 2006 to 2026
$8.1MTraining Program in Cardiovascular ResearchT32HL007374 · NHLBI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI MITTLEMAN, MURRAY A · 1985 to 2019
$7.9MAGRP NEURONS. NMDARs, Spines, Source of Excitatory Input and Downstream EffectorsR01DK096010 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI LOWELL, BRADFORD B · 2012 to 2024
$7.2MNeurocircuitry Underlying Leptin Regulation of Energy BalanceR01DK089044 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI LOWELL, BRADFORD B · 2010 to 2023
$6.0MDeciphering the functional role of MKRN3 in puberty and reproductionR01HD082314 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI Ursula B. Kaiser · 2015 to 2026
$5.7MReproductive physiology of gonadotropin synthesisR37HD019938 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI Ursula B. Kaiser · 2019 to 2026
$4.3MREPRODUCTIVE PHYSIOLOGY OF LUTROPIN SYNTHESISR01HD019938 · NICHD · JOSLIN DIABETES CENTER · PI KAISER, URSULA B. · 1985 to 2017
$3.9MFostering Research Mentorship & Training during Psychiatry Residency SupplementR25MH094612 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI FAVA, MAURIZIO, GREENFIELD, SHELLY F. · 2011 to 2022
$2.3MNCATS NIH HHS KL2 TR001100NCATS NIH HHS UL1 TR001102NHLBI NIH HHS 5T32HL007374-36NHLBI NIH HHS T32 HL007374NICHD NIH HHS R00 HD071970NICHD NIH HHS R01 HD019938NICHD NIH HHS R01 HD082314NICHD NIH HHS R01 HD090151NICHD NIH HHS R37 HD019938NIDDK NIH HHS P30 DK046200NIDDK NIH HHS P30 DK057521NIDDK NIH HHS R01 DK075632NIDDK NIH HHS R01 DK089044NIDDK NIH HHS R01 DK096010NIDDK NIH HHS R01 DK108797NIDDK NIH HHS R01 DK111401NIH HHS 5T32HL007374-36NIH HHS P30 DK046200NIH HHS P30 DK057521NIH HHS R00 HD071970NIH HHS R01 DK075632NIH HHS R01 DK089044NIH HHS R01 DK096010NIH HHS R01 DK111401NIH HHS R01 HD019938NIH HHS R01 HD082314NIH HHS R01 HD090151-A1NIMH NIH HHS R25 MH094612
Abstract
Pituitary adenylate cyclase activating polypeptide (PACAP,
Indexed as
AnimalsFemaleGonadotropin-Releasing HormoneKisspeptinsMaleMice, Inbred C57BLMice, KnockoutMice, TransgenicNeuronsPituitary Adenylate Cyclase-Activating PolypeptideReceptors, LeptinReproductionSex FactorsSexual MaturationVentromedial Hypothalamic NucleusGonadotropin-Releasing HormoneKISS1 protein, humanKisspeptinsPituitary Adenylate Cyclase-Activating PolypeptideReceptors, LeptinhypothalamuskisspeptinmouseneurosciencePACAPreproduction
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.