Evidence map›Paper›PMID 29905149›Full record

ArticleeLife2018

Group II intron inhibits conjugative relaxase expression in bacteria by mRNA targeting.

Guosheng Qu, Carol Lyn Piazza, Dorie Smith, Marlene Belfort

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Guosheng QuDepartment of Biological Sciences, University at Albany, Albany, United States.ORCID 0000-0002-0062-1929
Carol Lyn PiazzaDepartment of Biological Sciences, University at Albany, Albany, United States.
Dorie SmithDepartment of Biological Sciences, University at Albany, Albany, United States.
Marlene BelfortDepartment of Biological Sciences, University at Albany, Albany, United States.ORCID 0000-0002-1592-5618
University at Albany, State University of New York · US

Funding

SELF-SPLICING INTEINS: FUNCTION, EVOLUTION, APPLICATIONR01GM044844 · NIGMS · WADSWORTH CENTER · PI BELFORT, MARLENE · 1990 to 2019
$8.9M
SELF-SPLICING INTRONS IN THE PHAGE T4/E COLI SYSTEMR01GM039422 · NIGMS · WADSWORTH CENTER · PI BELFORT, MARLENE · 1988 to 2019
$5.3M
INTRON DYNAMICS IN BACTERIAR37GM039422 · NIGMS · WADSWORTH CENTER · PI BELFORT, MARLENE · 2001 to 2010
$4.0M
NIGMS NIH HHS R01 GM039422NIGMS NIH HHS R01 GM044844NIGMS NIH HHS R37 GM039422NIH HHS GM39422NIH HHS GM44844
6 · The paper itself

Abstract

Group II introns are mobile ribozymes that are rare in bacterial genomes, often cohabiting with various mobile elements, and seldom interrupting housekeeping genes. What accounts for this distribution has not been well understood. Here, we demonstrate that Ll.LtrB, the group II intron residing in a relaxase gene on a conjugative plasmid from

Indexed as

Conjugation, GeneticGene Expression Regulation, BacterialRNA SplicingBacterial ProteinsDNA Transposable ElementsEscherichia coliExonsGene Transfer, HorizontalInterspersed Repetitive SequencesIntronsLactococcus lactisPlasmidsRNA, MessengerSpliceosomesBacterial ProteinsDNA Transposable ElementsLtrB protein, Lactococcus lactisRNA, Messengerbiochemistrychemical biologyconjugationreverse splicingRNA-RNA interactionspliced exons reopening

Identifiers

PMID29905149
PMCPMC6003770
OpenAlexW2808401377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.