ReviewCurrent pain and headache reports2018
Relapsing Painful Ophthalmoplegic Neuropathy: No longer a "Migraine," but Still a Headache.
Review in Current pain and headache reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Diagnostic controversies in recurrent painful ophthalmoplegic neuropathy: single case report with a systematic review.Italian journal of pediatrics · 2022Pooled it
- A Case of Recurrent Painful Ophthalmoplegic Neuropathy with Frequent Relapses and Prophylaxis with High-Dose Vitamin B2 Supplementation.Neuro-ophthalmology (Aeolus Press) · 2026Article
- Recurrent painful ophthalmoplegic neuropathy: a cause for recurrent third nerve palsy in a child.BMJ case reports · 2021Article
- Bilateral persistent ophthalmoplegia in a patient with migraine: persistent migraine aura without infarction?BMJ case reports · 2021Article
- A Case of Recurrent Painful Ophthalmoplegic Neuropathy Successfully Treated with Beta-blocker Eye Drop Instillation.Neuro-ophthalmology (Aeolus Press) · 2021Article
- A Clinical Retrospective Study of Recurrent Painful Ophthalmoplegic Neuropathy in Adults.Journal of ophthalmology · 2021Article
- Recurrent alternating ophthalmoplegia with ipsilateral headache: unusual but possible manifestation of recurrent painful ophthalmoplegic neuropathy.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020Article
- Are some ophthalmoplegias migrainous in origin?Neurology. Clinical practice · 2019Article
- Recurrent Painful Ophthalmoplegic Neuropathy and Oculomotor Nerve Schwannoma: A Pediatric Case Report with Long-Term MRI Follow-Up and Literature Review.Pain research & management · 2019Review
- Recurrent Tolosa-Hunt syndrome.Tzu chi medical journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewRecurrent painful ophthalmoplegic neuropathy (RPON), formerly known as ophthalmoplegic migraine, is an uncommon disorder with repeated episodes of ocular cranial nerve neuropathy associated with ipsilateral headache. This review discusses the clinical presentation, current understanding of the pathophysiology, key differential diagnoses, and evaluation and treatment of RPON. RECENT
findingsThe literature is limited due to the rarity of the disorder. Recent case reports and series continue to suggest the age of first attack is most often during childhood or adolescence as well as a female predominance. Multiple recent case reports and series demonstrate focal enhancement of the affected cranial nerve, as the nerve root exits the brainstem. This finding contributed to the current classification of the disorder as a neuropathy, with the present understanding that it is due to a relapsing-remitting inflammatory or demyelinating process. The link to migraine remains a cause of disagreement in the literature. RPON is a complex disorder with features of inflammatory neuropathy and an unclear association with migraine. Regardless, the overall prognosis is good for individual episodes, but permanent nerve damage may accumulate with repeated attacks. A better understanding of the pathogenesis is needed to clarify whether it truly represents a single disorder and to guide its treatment. Until that time, a combined approach with acute and preventive therapies can mitigate acute symptoms as well as attempt to limit recurrence of this disabling syndrome.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.