Evidence map›Paper›PMID 29904818›Full record

ArticleEJNMMI research2018

PET imaging of

Sibel Isal, Julien Pierson, Laetitia Imbert, Alexandra Clement, Charlotte Collet, Sophie Pinel, Nicolas Veran, Aurélie Reinhard, Sylvain Poussier, Guillaume Gauchotte and 4 more

Open access · goldAbstract read
In one paragraph

Article in EJNMMI research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. The novel [RSC advances · 2026
    Article
  2. Article
  3. A comparison study of dynamic [Journal of cancer research and clinical oncology · 2024
    Article
  4. Fully Automated Macro- and Microfluidic Production of [Molecules (Basel, Switzerland) · 2022
    Article
  5. Article
  6. Unconventional non-amino acidic PET radiotracers for molecular imaging in gliomas.European journal of nuclear medicine and molecular imaging · 2021
    Review
  7. Article
  8. Review
  9. Article
  10. Synthesis of a DOTA-RSC advances · 2021
    Article
  11. [European journal of nuclear medicine and molecular imaging · 2021
    Article
  12. Evaluation of NanotargetedInternational journal of molecular sciences · 2021
    Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Sibel IsalDepartment of Nuclear Medicine, CHRU-Nancy, F-54000, Nancy, France.
Julien PiersonNancyclotep Molecular and Experimental Imaging Platform, CHRU-Nancy, Lorraine University, Nancy, F-54000, France.
Laetitia ImbertDepartment of Nuclear Medicine, CHRU-Nancy, F-54000, Nancy, France.
Alexandra ClementNancyclotep Molecular and Experimental Imaging Platform, CHRU-Nancy, Lorraine University, Nancy, F-54000, France.
Charlotte ColletNancyclotep Molecular and Experimental Imaging Platform, CHRU-Nancy, Lorraine University, Nancy, F-54000, France.
Sophie PinelLorraine University, CNRS, CRAN, UMR 7039, 9, avenue de la forêt de Haye, 54000, Nancy, France.
Nicolas VeranDepartment of Nuclear Medicine, CHRU-Nancy, F-54000, Nancy, France.
Aurélie ReinhardNancyclotep Molecular and Experimental Imaging Platform, CHRU-Nancy, Lorraine University, Nancy, F-54000, France.
Sylvain PoussierNancyclotep Molecular and Experimental Imaging Platform, CHRU-Nancy, Lorraine University, Nancy, F-54000, France.
Guillaume GauchotteDepartment of Pathology, CHRU-Nancy, Université de Lorraine, 9, avenue de la forêt de Haye, F-54000, Nancy, France.
Steeven FrezierNancyclotep Molecular and Experimental Imaging Platform, CHRU-Nancy, Lorraine University, Nancy, F-54000, France.
Gilles KarcherDepartment of Nuclear Medicine, CHRU-Nancy, F-54000, Nancy, France.
Pierre-Yves MarieDepartment of Nuclear Medicine, CHRU-Nancy, F-54000, Nancy, France.
Fatiha MaskaliNancyclotep Molecular and Experimental Imaging Platform, CHRU-Nancy, Lorraine University, Nancy, F-54000, France. f.maskali@nancyclotep.com.
Inserm · FRUniversité de Lorraine · FRCentre de Médecine Préventive · FRCentre d’Investigation Clinique Innovation Technologique de Nancy · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTracers triggering αvβ3 integrins, such as certain RGD-containing peptides, were found promising in previous pilot studies characterizing high-grade gliomas. However, only limited comparisons have been performed with current PET tracers. This study aimed at comparing the biodistribution of

methodsNude rodents bearing human U87-MG glioblastoma tumor xenografts in the flank (34 tumors in mice) or in the brain (5 tumors in rats) were analyzed. Kinetics of

resultsBoth tracers showed a primary renal route of clearance, although with faster clearance for

conclusions

Indexed as

18F-FDG68Ga-NODAGA-RGDGlioblastomaPETαvβ3 integrin

Identifiers

PMID29904818
PMCPMC6003898
OpenAlexW2808589941

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.