Evidence map›Paper›PMID 29904356›Full record

ArticleFrontiers in physiology2018

Coronary Blood Flow Is Increased in RV Hypertrophy, but the Shape of Normalized Waves Is Preserved Throughout the Arterial Tree.

Yunlong Huo, Ghassan S Kassab

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 3 countries.

Yunlong HuoPKU-HKUST Shenzhen-Hongkong Institution, Shenzhen, China.
Ghassan S KassabCalifornia Medical Innovations Institute, San Diego, CA, United States.
California Medical Innovations Institute · USHong Kong University of Science and Technology · HK

Funding

Coronary Blood Flow: Integrated Theory and ExperimentsU01HL118738 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BEARD, DANIEL A, KASSAB, GHASSAN S · 2013 to 2018
$3.4M
Roles of Ischemia and mechanical dyssynchrony in optimizing CRT responsesR01HL134841 · NHLBI · MICHIGAN STATE UNIVERSITY · PI KASSAB, GHASSAN S, LEE, LIK CHUAN · 2017 to 2020
$2.3M
NHLBI NIH HHS R01 HL134841NHLBI NIH HHS U01 HL118738
6 · The paper itself

Abstract

A pulsatile hemodynamic analysis was carried out in the right coronary arterial (RCA) tree of control and RV hypertrophy (RVH) hearts. The shape of flow and wall shear stress (WSS) waves was hypothesized to be maintained throughout the RCA tree in RVH (i.e., similar patterns of normalized flow and WSS waves in vessels of various sizes). Consequently, we reconstructed the entire RCA tree down to the first capillary bifurcation of control and RVH hearts based on measured morphometric data. A Womersley-type model was used to compute the flow and WSS waves in the tree. The hemodynamic parameters obtained from experimental measurements were incorporated into the numerical model. Given an increased number of arterioles, the mean and amplitude of flow waves at the inlet of RCA tree in RVH was found to be two times larger than that in control, but no significant differences (

Indexed as

pulsatile flowPulsatile wall shear stressright coronary arterial treeright ventricular hypertrophyWomersley-type model

Identifiers

PMID29904356
PMCPMC5990630
OpenAlexW2804710928

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.