Evidence map›Paper›PMID 29904141›Full record

Trial reportScientific reports2018

Distribution of reported syphilis cases in South China: spatiotemporal analysis.

Ngai Sze Wong, Lei Chen, Joseph D Tucker, Peizhen Zhao, Beng Tin Goh, Chin Man Poon, Ligang Yang, Bin Yang, Heping Zheng, Shujie Huang

Open access · goldAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Estimating the direct medical cost of syphilis in China.Archives of dermatological research · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. CONGENITAL SYPHILIS IN THE PARAÍBA VALLEY USING A SPATIAL APPROACH.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2020
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 4 countries.

Ngai Sze WongInstitute for Global Health & Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0003-3788-8114
Lei ChenDermatology Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Joseph D TuckerInstitute for Global Health & Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Peizhen ZhaoDermatology Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Beng Tin GohGuangdong Provincial Dermatology Hospital, Guangzhou, Guangdong, China.
Chin Man PoonStanley Ho Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Hong Kong, China.
Ligang YangDermatology Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Bin YangDermatology Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Heping ZhengDermatology Hospital, Southern Medical University, Guangzhou, Guangdong, China. zhhpf@hotmail.com.
Shujie HuangDermatology Hospital, Southern Medical University, Guangzhou, Guangdong, China. huangshj_jm@126.com.
Guangdong Provincial People's Hospital · CNUniversity of North Carolina at Chapel Hill · USChinese University of Hong Kong · HKGuangdong Provincial Hospital of Traditional Chinese Medicine · CNRoyal London Hospital · GB

Funding

Spurring Innovation in HIV Testing and Linkage: A Crowdsourcing Approach -Diversity SupplementR01AI114310 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI TUCKER, JOSEPH DAVID, WEI, CHONGYI · 2014 to 2018
$3.3M
UNC-South China STD Research Training CenterD43TW009532 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COHEN, MYRON SCOTT, TUCKER, JOSEPH DAVID · 2013 to 2017
$1.3M
FIC NIH HHS D43 TW009532NIAID NIH HHS R01 AI114310
6 · The paper itself

Abstract

There was a varied spatial distribution of reported syphilis cases across cities in South China. This study aims to identify and describe spatiotemporal clusters of primary and secondary syphilis (P/S) cases in this region. Reported syphilis cases in Guangdong Province, China, from January 2014 to June 2015 were collected from the national centralized reporting system. Spatiotemporal clusters of P/S were identified and cross-validated by calculating local Moran's I, performing hotspot analysis (Getis-Ord Gi*), and constructing a discrete Poisson model in SaTScan. Reported cases within and outside the clusters were compared by bivariable and multivariable logistic regression. Out of 17,691 reported P/S cases, 11% were in the identified spatiotemporal clusters. The monthly P/S notification rate (per 100,000 persons) ranged between 0.6 and 1. The identified clusters were located in 14, out of 126, counties in eight, out of 21, cities. Cases of older age, living in rural area and taking self-initiated syphilis test were more likely to be in the clusters. Some areas bore a greater burden of P/S in Guangdong Province. Routine spatiotemporal analysis of P/S cases may be useful for enhancing syphilis control programs by strategic location-based service planning.

Indexed as

Rural PopulationAdultAge FactorsChinaFemaleHumansMaleMiddle AgedSyphilis

Identifiers

PMID29904141
PMCPMC6002518
OpenAlexW2806176474

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.