Evidence map›Paper›PMID 29904031›Full record

ReviewJournal of clinical medicine2018

Immunotherapy in Non-Small Cell Lung Cancer: Shifting Prognostic Paradigms.

Megan B Barnet, Wendy A Cooper, Michael J Boyer, Steven Kao

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. The mPharmaceuticals (Basel, Switzerland) · 2023
    Article
  4. Article
  5. A NovelJournal of immunology research · 2022
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Megan B BarnetThe Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia. m.barnet@garvan.org.au.ORCID 0000-0003-3243-2716
Wendy A CooperSydney Medical School, The University of Sydney, Camperdown, NSW 2006, Australia. wendy.cooper@health.nsw.gov.au.
Michael J BoyerSydney Medical School, The University of Sydney, Camperdown, NSW 2006, Australia. michael.boyer@lh.org.au.
Steven KaoSydney Medical School, The University of Sydney, Camperdown, NSW 2006, Australia. steven.kao@lh.org.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune checkpoint inhibitors have shown efficacy in the treatment of non-small cell lung cancer (NSCLC) in the adjuvant, first- and subsequent-line settings. In metastatic disease, they provide hope of durable response where “best-case” scenario has long been inadequate. This progress has highlighted the immunogenic nature of NSCLC and invigorated research into immunotherapy in the field. In this review we consider the foundations of immunotherapy in NSCLC, canvass the current research and summarise the evidence guiding clinical practice.

Indexed as

checkpoint inhibitorsimmunotherapynon-small cell lung cancer

Identifiers

PMID29904031
PMCPMC6024943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.