ArticleInternational journal of environmental research and public health2018
Tuberculosis Specific Interferon-Gamma Production in a Current Refugee Cohort in Western Europe.
Article in International journal of environmental research and public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 7 citations in OpenAlex.
- [Positive interferon-gamma release assay and immunosuppression: guideline-based diagnosis and treatment of tuberculosis infection].Innere Medizin (Heidelberg, Germany) · 2026Article
- Disease burden in a large cohort of asylum seekers and refugees in Germany.Journal of global health · 2021Article
- Tuberculosis screening during the 2015 European refugee crisis.BMC public health · 2020Article
- Health of Refugees and Migrants-Where Do We Stand and What Directions Should We Take?International journal of environmental research and public health · 2019Article
- Tuberculous coxitis with trochanteric bursitis manifesting a year after immigration to Germany: a case report.Journal of medical case reports · 2018Article
- Pregnancy Related Health Care Needs in Refugees-A Current Three Center Experience in Europe.International journal of environmental research and public health · 2018Article
Corrections and comments
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn 2015, a high number of refugees with largely unknown health statuses immigrated to Western Europe. To improve caretaking strategies, we assessed the prevalence of latent tuberculosis infection (LTBI) in a refugee cohort.
methodsInterferon-Gamma release assays (IGRA, Quantiferon) were performed in
resultsMost refugees were young, male adults. Overall, IGRA testing was positive in 17.9% (95% CI = 13.2⁻23.5%) of subjects. Positivity rates increased with age (0% <18 years versus 46.2% >50 years). Age was the only factor significantly associated with a positive IGRA in multiple regression analysis including gender, C reactive protein, hemoglobin, leukocyte, and thrombocyte count and lymphocyte, monocyte, neutrophil, basophil, and eosinophil fraction. For one year change in age, the odds are expected to be 1.06 times larger, holding all other variables constant (
conclusionObserved LTBI frequencies are lower than previously reported in similar refugee cohorts. However, as elderly people are at higher risk for developing active tuberculosis, the observed high rate of LTBI in senior refugees emphasizes the need for new policies on the detection and treatment regimens in this group.
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