ArticleAJNR. American journal of neuroradiology2018
Prognostic Implications of Gadolinium Enhancement of Skull Base Chordomas.
Article in AJNR. American journal of neuroradiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 22 citations in OpenAlex.
- CT perfusion-focused preoperative assessment of the blood-supplying state among imaging modalities in skull base chordoma: a retrospective single-center cohort.Journal of neuro-oncology · 2026Article
- Lower Cervical Chordomas: A Case Report and Differential Diagnosis.Cancer reports (Hoboken, N.J.) · 2025Article
- Muscle metastasis from cervical chordoma: a case report.Skeletal radiology · 2025Article
- Surgical management of skull base and spinal chordomas: A case series with comprehensive review of the literature.North American Spine Society journal · 2024Article
- Low-dose GBCA administration for brain tumour dynamic contrast enhanced MRI: a feasibility study.Scientific reports · 2024Article
- Imaging of pituitary tumors: an update with the 5th WHO Classifications-part 2. Neoplasms other than PitNET and tumor-mimicking lesions.Japanese journal of radiology · 2023Review
- Differences in stromal component of chordoma are associated with contrast enhancement in MRI and differential gene expression in RNA sequencing.Scientific reports · 2022Article
- Chordoma-Current Understanding and Modern Treatment Paradigms.Journal of clinical medicine · 2021Review
- Peri-operative prognostic factors for primary skull base chordomas: results from a single-center cohort.Acta neurochirurgica · 2021Article
- The CT guided transoral approach: A biopsy technique for a poorly differentiated chordoma in a 5 year old.Journal of radiology case reports · 2021Article
- Exophytic Lumbar Vertebral Body Mass in an Adult with Back Pain.AJNR. American journal of neuroradiology · 2020Article
- Skull base chordomas review of current treatment paradigms.World journal of otorhinolaryngology - head and neck surgery · 2020Review
- MRI Signal Intensity and Electron Ultrastructure Classification Predict the Long-Term Outcome of Skull Base Chordomas.AJNR. American journal of neuroradiology · 2020Article
Corrections and comments
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Authors and funding
5 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeSkull base chordomas often demonstrate variable MR imaging characteristics, and there has been limited prior research investigating the potential clinical relevance of this variability. The purpose of this retrospective study was to assess the prognostic implications of signal intensity on standard imaging techniques for the biologic behavior of skull base chordomas. MATERIALS AND
methodsMedical records were retrospectively reviewed for 22 patients with pathologically confirmed skull base chordomas. Clinical data were recorded, including the degree of surgical resection, the presence or absence of radiation therapy, and time to progression/recurrence of the tumor or time without progression/recurrence of the tumor following initial treatment. Pretreatment imaging was reviewed for the presence or absence of enhancement and the T2 signal characteristics. Tumor-to-brain stem signal intensity ratios on T2, precontrast T1, and postcontrast T1 spin-echo sequences were also calculated. Statistical analysis was then performed to assess correlations between imaging characteristics and tumor progression/recurrence.
resultsProgression/recurrence of skull base chordomas was seen following surgical resection in 11 of 14 (78.6%) patients with enhancing tumors and in zero of 8 patients with nonenhancing tumors. There was a statistically significant correlation between skull base chordoma enhancement and subsequent tumor progression/recurrence (
conclusionsEnhancement of skull base chordomas is a risk factor for tumor progression/recurrence following surgical resection.
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