Evidence map›Paper›PMID 29903915›Full record

ArticleThe Journal of biological chemistry2018

The RNA-binding complex ESCRT-II in

Amy B Emerman, Michael D Blower

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Amy B EmermanFrom the Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts 02114 and the Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115.
Michael D BlowerFrom the Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts 02114 and the Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115 blower@molbio.mgh.harvard.edu.ORCID 0000-0002-5037-1972
Massachusetts General Hospital · US

Funding

Analysis of microtubule localized RNAsR01GM086434 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI BLOWER, MICHAEL DEMIAN · 2009 to 2013
$1.6M
NIGMS NIH HHS R01 GM086434
6 · The paper itself

Abstract

RNA-binding proteins (RBP) are critical regulators of gene expression. Recent studies have uncovered hundreds of mRNA-binding proteins that do not contain annotated RNA-binding domains and have well-established roles in other cellular processes. Investigation of these nonconventional RBPs is critical for revealing novel RNA-binding domains and may disclose connections between RNA regulation and other aspects of cell biology. The endosomal sorting complex required for transport II (ESCRT-II) is a nonconventional RNA-binding complex that has a canonical role in multivesicular body formation. ESCRT-II was identified previously as an RNA-binding complex in

Indexed as

AnimalsEndosomal Sorting Complexes Required for TransportFemaleOvumProtein SubunitsPurinesRNARNA-Binding ProteinsXenopus laevisEndosomal Sorting Complexes Required for TransportProtein SubunitsPurinesRNARNA-Binding Proteinsendocytosisendosome maturationESCRT-IIGA-rich sequencemembrane traffickingpolypurine motifRNARNA-binding proteinRNA localizationRNA metabolismRNA–protein interaction

Identifiers

PMID29903915
PMCPMC6093225
OpenAlexW2808234282

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.