Evidence map›Paper›PMID 29903909›Full record

ArticleThe Journal of biological chemistry2018

Binding to small ubiquitin-like modifier and the nucleolar protein Csm1 regulates substrate specificity of the Ulp2 protease.

Claudio Ponte de Albuquerque, Raymond T Suhandynata, Christopher R Carlson, Wei-Tsung Yuan, Huilin Zhou

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Multifaceted roles of SUMO in DNA metabolism.Nucleus (Austin, Tex.) · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Claudio Ponte de AlbuquerqueLudwig Institute for Cancer Research, San Diego Branch, University of California, San Diego, La Jolla, California 92093.
Raymond T SuhandynataLudwig Institute for Cancer Research, San Diego Branch, University of California, San Diego, La Jolla, California 92093.
Christopher R CarlsonLudwig Institute for Cancer Research, San Diego Branch, University of California, San Diego, La Jolla, California 92093.
Wei-Tsung YuanLudwig Institute for Cancer Research, San Diego Branch, University of California, San Diego, La Jolla, California 92093; Division of Biological Sciences, University of California, San Diego, La Jolla, California 92093.
Huilin ZhouLudwig Institute for Cancer Research, San Diego Branch, University of California, San Diego, La Jolla, California 92093; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, California 92093; Moores Cancer Center, University of California, San Diego, La Jolla, California 92093. Electronic address: huzhou@ucsd.edu.
University of California San Diego · US

Funding

Contemporary Approaches to Cancer Cell Signaling and CommunicationT32CA009523 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DONOGHUE, DANIEL J, YANG, JING · 1985 to 2025
$12.1M
Suppression of duplication-mediated genome rearrangements by protein sumoylationR01GM116897 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ZHOU, HUILIN · 2015 to 2023
$2.6M
Regulation of Receptor Tyrosine KinasesR01GM065490 · NIGMS · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI DONOGHUE, DANIEL J · 2002 to 2005
$1.0M
Orbitrap Fusion Mass SpectrometerS10OD023498 · OD · LUDWIG INSTITUTE FOR CANCER RES LTD · PI ZHOU, HUILIN · 2017 to 2017
$600k
NCI NIH HHS T32 CA009523NIGMS NIH HHS R01 GM065490NIGMS NIH HHS R01 GM116897NIH HHS S10 OD023498
6 · The paper itself

Abstract

Ulp1 and Ulp2, in the yeast

Indexed as

Protein Processing, Post-TranslationalAmino Acid SequenceBinding SitesCell Cycle ProteinsCell NucleusCysteine EndopeptidasesEndopeptidasesGene Expression Regulation, FungalKineticsNuclear ProteinsProtein BindingProtein Interaction Domains and MotifsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSequence AlignmentSequence Homology, Amino AcidCell Cycle ProteinsCSM1 protein, S cerevisiaeCysteine EndopeptidasesEndopeptidasesNuclear ProteinsSaccharomyces cerevisiae ProteinsUbiquitinULP1 protein, S cerevisiaeULP2 protein, S cerevisiaeCdc14isothermal titration calorimetry (ITC)Net1post-translational modification (PTM)proteasesubstrate specificitySUMO-interacting motif (SIM)sumoylationTof2Ulp1Ulp2

Identifiers

PMID29903909
PMCPMC6078457
OpenAlexW2807984629

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.