Evidence map›Paper›PMID 29903905›Full record

ArticleJournal of neurology, neurosurgery, and psychiatry2018

Idiopathic intracranial hypertension: consensus guidelines on management.

Susan P Mollan, Brendan Davies, Nick C Silver, Simon Shaw, Conor L Mallucci, Benjamin R Wakerley, Anita Krishnan, Swarupsinh V Chavda, Satheesh Ramalingam, Julie Edwards and 8 more

Abstract readConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurology, neurosurgery, and psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 295 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
295citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

295 citing papers in PubMed, 10 syntheses or guidelines pooled it.

  1. Therapeutic role of GLP-1 receptor agonists in idiopathic intracranial hypertension: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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235 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Susan P MollanMetabolic Neurology, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.ORCID 0000-0002-6314-4437
Brendan DaviesDepartment of Neurology, University Hospital North Midlands NHS Trust, Stoke-on-Trent, UK.
Nick C SilverDepartment of Neurology, The Walton Centre NHS Foundation Trust, Liverpool, UK.
Simon ShawDepartment of Neurosurgery, University Hospital North Midlands NHS Trust, Royal Stoke University Hospital, Stoke-on-Trent, UK.
Conor L MallucciDepartment of Neurosurgery, The Walton Centre NHS Foundation Trust, Liverpool, UK.
Benjamin R WakerleyDepartment of Neurology, Gloucestershire Hospitals NHS Foundation Trust, Cheltenham, UK.
Anita KrishnanDepartment of Neurology, The Walton Centre NHS Foundation Trust, Liverpool, UK.
Swarupsinh V ChavdaDepartment of Neuroradiology, University Hospitals Birmingham, Queen Elizabeth Hospital, Birmingham, UK.
Satheesh RamalingamDepartment of Neuroradiology, University Hospitals Birmingham, Queen Elizabeth Hospital, Birmingham, UK.
Julie EdwardsDepartment of Neurology, Sandwell and West Birmingham NHS Trust, Birmingham, UK.
Krystal HemmingsIIH-UK charity, Tyne & Wear, UK.
Michelle WilliamsonIIH-UK charity, Tyne & Wear, UK.
Michael A BurdonBirmingham Neuro-Ophthalmology, Queen Elizabeth Hospital, Birmingham, UK.
Ghaniah Hassan-SmithMetabolic Neurology, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.
Kathleen DigreDepartments of Ophthalmology and Neurology, Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.
Grant T LiuNeuro-ophthalmology Services, Children's Hospital of Philadelphia and Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Rigmor Højland JensenDanish Headache Center, Department of Neurology, Rigshospitalet-Glostrup, University of Copenhagen, Copenhagen, Denmark.
Alexandra J SinclairMetabolic Neurology, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.ORCID 0000-0002-6314-4437

Funding

Department of Health NIHR-CS-011-028Medical Research Council MR/K015184/1Wellcome Trust
6 · The paper itself

Abstract

The aim was to capture interdisciplinary expertise from a large group of clinicians, reflecting practice from across the UK and further, to inform subsequent development of a national consensus guidance for optimal management of idiopathic intracranial hypertension (IIH).

methodsBetween September 2015 and October 2017, a specialist interest group including neurology, neurosurgery, neuroradiology, ophthalmology, nursing, primary care doctors and patient representatives met. An initial UK survey of attitudes and practice in IIH was sent to a wide group of physicians and surgeons who investigate and manage IIH regularly. A comprehensive systematic literature review was performed to assemble the foundations of the statements. An international panel along with four national professional bodies, namely the Association of British Neurologists, British Association for the Study of Headache, the Society of British Neurological Surgeons and the Royal College of Ophthalmologists critically reviewed the statements.

resultsOver 20 questions were constructed: one based on the diagnostic principles for optimal investigation of papilloedema and 21 for the management of IIH. Three main principles were identified: (1) to treat the underlying disease; (2) to protect the vision; and (3) to minimise the headache morbidity. Statements presented provide insight to uncertainties in IIH where research opportunities exist.

conclusionsIn collaboration with many different specialists, professions and patient representatives, we have developed guidance statements for the investigation and management of adult IIH.

Indexed as

HeadachePseudotumor CerebriHumansSystematic Reviews as Topicbenign intracran hypclinical neurologyheadacheneuroophthalmologyneurosurgery

Identifiers

PMID29903905
PMCPMC6166610

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.