Evidence map›Paper›PMID 29903864›Full record

ArticleBiology open2018

Spatio-temporal neural stem cell behavior leads to both perfect and imperfect structural brain regeneration in adult newts.

Yuko Urata, Wataru Yamashita, Takeshi Inoue, Kiyokazu Agata

Open access · goldAbstract read
In one paragraph

Article in Biology open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Organ Regeneration Without Relying on Regeneration-Dedicated Stem Cells.Results and problems in cell differentiation · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Model systems for regeneration: salamanders.Development (Cambridge, England) · 2019
    Review
  11. Article
  12. Bioscaffold-Induced Brain Tissue Regeneration.Frontiers in neuroscience · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yuko UrataDepartment of Biophysics, Graduate School of Science, Kyoto University, Kyoto, 606-8502, Japan urata.yuko.73s@kyoto-u.jp kiyokazu.agata@gakushuin.ac.jp.ORCID http://orcid.org/0000-0002-1808-6784
Wataru YamashitaDepartment of Biophysics, Graduate School of Science, Kyoto University, Kyoto, 606-8502, Japan.
Takeshi InoueDepartment of Biophysics, Graduate School of Science, Kyoto University, Kyoto, 606-8502, Japan.ORCID http://orcid.org/0000-0003-3289-4478
Kiyokazu AgataDepartment of Biophysics, Graduate School of Science, Kyoto University, Kyoto, 606-8502, Japan urata.yuko.73s@kyoto-u.jp kiyokazu.agata@gakushuin.ac.jp.ORCID http://orcid.org/0000-0002-5195-2576
Kyoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adult newts can regenerate large parts of their brain from adult neural stem cells (NSCs), but how adult NSCs reorganize brain structures during regeneration remains unclear. In development, elaborate brain structures are produced under broadly coordinated regulations of embryonic NSCs in the neural tube, whereas brain regeneration entails exquisite control of the re-establishment of certain brain parts, suggesting that a yet-unknown mechanism directs NSCs upon partial brain excision. Here we report that upon excision of a quarter of the adult newt (

Indexed as

Central nervous systemNeural stem cellsNeurogenesisRegeneration

Identifiers

PMID29903864
PMCPMC6031346
OpenAlexW2808295998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.