ArticleHaematologica2018
Circulating iron levels influence the regulation of hepcidin following stimulated erythropoiesis.
Article in Haematologica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 34 citations in OpenAlex.
- Effects of altitude and recombinant human erythropoietin on iron metabolism: a randomized controlled trial.American journal of physiology. Regulatory, integrative and comparative physiology · 2021Trial
- Systemic Iron Metabolism.Advances in experimental medicine and biology · 2025Review
- Article
- A Decrease in Maternal Iron Levels Is the Predominant Factor Suppressing Hepcidin during Pregnancy in Mice.International journal of molecular sciences · 2023Article
- Article
- The mutual crosstalk between iron and erythropoiesis.International journal of hematology · 2022Review
- Characterization of acquired anemia in children by iron metabolism parameters.Scientific reports · 2022Article
- Effect of Erythropoietin on the Expression of Murine Transferrin Receptor 2.International journal of molecular sciences · 2021Article
- Erythroferrone structure, function, and physiology: Iron homeostasis and beyond.Journal of cellular physiology · 2021Review
- Physiological and pathophysiological mechanisms of hepcidin regulation: clinical implications for iron disorders.British journal of haematology · 2021Review
- Matriptase-2 and Hemojuvelin in Hepcidin Regulation: In Vivo Immunoblot Studies inInternational journal of molecular sciences · 2021Article
- NCOA4-mediated ferritinophagy in macrophages is crucial to sustain erythropoiesis in mice.Haematologica · 2021Article
- Induction of erythroferrone in healthy humans by micro-dose recombinant erythropoietin or high-altitude exposure.Haematologica · 2021Article
- Review
- The diagnostic potential of the iron-regulatory hormone hepcidin.HemaSphere · 2019Article
- The Importance of Iron Status for Young Children in Low- and Middle-Income Countries: A Narrative Review.Pharmaceuticals (Basel, Switzerland) · 2019Review
- Transient decrease of serum iron after acute erythropoietin treatment contributes to hepcidin inhibition by ERFE in mice.Haematologica · 2019Article
- Liver iron sensing and body iron homeostasis.Blood · 2019Review
- Effect of stimulated erythropoiesis on liver SMAD signaling pathway in iron-overloaded and iron-deficient mice.PloS one · 2019Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The stimulation of erythrocyte formation increases the demand for iron by the bone marrow and this in turn may affect the levels of circulating diferric transferrin. As this molecule influences the production of the iron regulatory hormone hepcidin, we hypothesized that erythropoiesis-driven changes in diferric transferrin levels could contribute to the decrease in hepcidin observed following the administration of erythropoietin. To examine this, we treated mice with erythropoietin and examined diferric transferrin at various time points up to 18 hours. We also investigated the effect of altering diferric transferrin levels on erythropoietin-induced inhibition of
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