Evidence map›Paper›PMID 29903604›Full record

ArticleMayo Clinic proceedings2018

Racial Differences in the Association Between Nonexercise Estimated Cardiorespiratory Fitness and Incident Stroke.

Xuemei Sui, Virginia J Howard, Michelle N McDonnell, Linda Ernstsen, Matthew L Flaherty, Steven P Hooker, Carl J Lavie

Abstract read
In one paragraph

Article in Mayo Clinic proceedings, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 3 countries.

Xuemei SuiDepartment of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia. Electronic address: msui@mailbox.sc.edu.
Virginia J HowardDepartment of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham.
Michelle N McDonnellAlliance for Research in Exercise, Nutrition and Activity, Sansom Institute for Health Research, University of South Australia, Adelaide, Australia.
Linda ErnstsenDepartment of Public Health and Nursing, Faculty of Medicine and Health Science, Norwegian University of Science and Technology, Trondheim, Norway.
Matthew L FlahertyDepartment of Neurology, University of Cincinnati College of Medicine, Cincinnati, OH.
Steven P HookerCollege of Health Solutions, Arizona State University, Phoenix.
Carl J LavieDepartment of Cardiovascular Diseases, John Ochsner Health and Vascular Institute, Ochsner Clinical School - The University of Queensland School of Medicine, New Orleans, LA.
Arizona State University · USNorwegian University of Science and Technology · NOOchsner Health System · USUniversity of Alabama at Birmingham · USUniversity of Cincinnati Medical Center · USUniversity of South Australia · AUUniversity of South Carolina · US

Funding

VCID and Stroke in a Bi-racial National CohortU01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CUSHMAN, MARY, HOWARD, GEORGE · 2002 to 2022
$96.0M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5M
Understanding Cohort Effects on Stroke, VCID, and Cognition After Major Epidemiologic TransitionsR01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MARY CUSHMAN, VIRGINIA J. HOWARD · 2001 to 2026
$8.8M
NIDDK NIH HHS P30 DK079626NINDS NIH HHS R01 NS041588NINDS NIH HHS U01 NS041588
6 · The paper itself

Abstract

objectiveTo examine the association between estimated cardiorespiratory fitness (eCRF) and incident stroke by black and white race. PARTICIPANTS AND

methodsA total of 24,162 participants from the REasons for Geographic And Racial Differences in Stroke study (13,232 [54.8%] women; 9543 [39.5%] blacks; mean age, 64.6±9.3 years) without stroke at enrollment between January 15, 2003, and October 30, 2007, were followed for incident stroke through March 31, 2016. Baseline eCRF in maximal metabolic equivalents was determined using nonexercise sex-specific algorithms and further grouped into age- and sex-specific tertiles.

resultsOver a mean of 8.3±3.2 years of follow-up, 945 (3.9%) incident strokes occurred (377 in blacks and 568 in whites). The association between eCRF and stroke risk differed significantly by race (P

conclusionEstimated cardiorespiratory fitness measured using nonexercise equations is a useful predictor of stroke in whites. The lack of an overall association between eCRF and stroke risk in blacks suggests that the assessment of eCRF in blacks may not be helpful in primary stroke prevention.

Indexed as

Cardiorespiratory FitnessAgedBlack or African AmericanCohort StudiesFemaleHumansIncidenceMaleMiddle AgedRisk FactorsStrokeWhite People

Identifiers

PMID29903604
PMCPMC6154797
OpenAlexW2807846948

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.