Evidence map›Paper›PMID 29903569›Full record

ArticleEBioMedicine2018

Loss of Cardio-Protective Effects at the CDH13 Locus Due to Gene-Sleep Interaction: The BCAMS Study.

Ge Li, Dan Feng, Yonghui Wang, Junling Fu, Lanwen Han, Lujiao Li, Struan F A Grant, Mingyao Li, Ming Li, Shan Gao

Abstract read
In one paragraph

Article in EBioMedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Ge LiDepartment of Endocrinology, Key Laboratory of Endocrinology, National Health and Family Planning Commission, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing 100730, China.
Dan FengDepartment of Endocrinology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100043, China.
Yonghui WangDepartment of Endocrinology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100043, China.
Junling FuDepartment of Endocrinology, Key Laboratory of Endocrinology, National Health and Family Planning Commission, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing 100730, China.
Lanwen HanDepartment of Endocrinology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100043, China.
Lujiao LiDepartment of Endocrinology, Key Laboratory of Endocrinology, National Health and Family Planning Commission, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing 100730, China.
Struan F A GrantDivision of Endocrinology, The Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania; Philadelphia, PA 19104, USA; Division of Human Genetics, The Children's Hospital of Philadelphia Research Institute, Philadelphia, PA 19104, USA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Mingyao LiDepartments of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Ming LiDepartment of Endocrinology, Key Laboratory of Endocrinology, National Health and Family Planning Commission, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing 100730, China. Electronic address: liming@pumch.cn.
Shan GaoDepartment of Endocrinology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100043, China. Electronic address: gaoshanmw@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Left ventricular mass index (LVMI) provides a metric for cardiovascular disease risk. We aimed to assess the association of adiponectin-related genetic variants resulting from GWAS in East Asians (loci in/near CDH13, ADIPOQ, WDR11FGF, CMIP and PEPD) with LVMI, and to examine whether sleep duration modified these genetic associations in youth. The 559 subjects aged 15-28 years were recruited from the Beijing Child and Adolescent Metabolic Syndrome study. Among the six loci, CDH13 rs4783244 was significantly correlated with adiponectin levels (p = 8.07 × 10

Indexed as

AdolescentAdultCadherinsCardiovascular DiseasesFemaleGenetic Association StudiesHeart VentriclesHumansMaleMetabolic SyndromeRisk FactorsSleepYoung AdultCadherinsH-cadherinAdiponectinAdiponectin-associated locusCDH13Left ventricular mass indexSleep time

Identifiers

PMID29903569
PMCPMC6020797

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.