Evidence map›Paper›PMID 29902956›Full record

ArticleJournal of empirical research on human research ethics : JERHRE2018

The Real-Time IRB: A Collaborative Innovation to Decrease IRB Review Time.

Ryan Spellecy, Ann Marie Eve, Emily R Connors, Reza Shaker, David C Clark

Abstract read
In one paragraph

Article in Journal of empirical research on human research ethics : JERHRE, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Responses to Commentaries on "Ethics as if Your Life Depended on It".Journal of empirical research on human research ethics : JERHRE · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. COVID-19 pandemic response varies by clinical trial sponsor type.Journal of clinical and translational science · 2021
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ryan Spellecy1 Medical College of Wisconsin, Milwaukee, USA.
Ann Marie Eve1 Medical College of Wisconsin, Milwaukee, USA.
Emily R Connors1 Medical College of Wisconsin, Milwaukee, USA.
Reza Shaker1 Medical College of Wisconsin, Milwaukee, USA.
David C Clark1 Medical College of Wisconsin, Milwaukee, USA.

Funding

Clinical and Translational Science AwardUL1TR001436 · NCATS · MEDICAL COLLEGE OF WISCONSIN · PI FREED, JULIE K · 2015 to 2025
$47.5M
NCATS NIH HHS UL1 TR001436
6 · The paper itself

Abstract

Lengthy review times for institutional review boards (IRBs) are a well-known barrier to research. In response to numerous calls to reduce review times, we devised "Real-Time IRB," a process that drastically reduces IRB review time. In this, investigators and study staff attend the IRB meeting and make changes to the protocol while the IRB continues its meeting, so that final approval can be issued at the meeting. This achieved an overall reduction in time from submission to the IRB to final approval of 40%. While this process is time and resource intensive, and cannot address all delays in research, it shows great promise for increasing the pace by which research is translated to patient care.

Indexed as

EfficiencyEthical ReviewEthics Committees, ResearchBiomedical ResearchCooperative BehaviorEthics, ResearchHumansResearch Personnelassessmentclinical trialscollaborationevaluationevaluation researchIRBIRB performancequalityresearch ethics committee

Identifiers

PMID29902956
PMCPMC6146014

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.