ArticleJournal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer2018
Development and Validation of a Nomogram Prognostic Model for SCLC Patients.
Article in Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 133 papers.
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Who cites it
133 citing papers in PubMed.
- Web-based nomograms for predicting overall survival and cancer-specific survival in retroperitoneal leiomyosarcoma: a population-based analysis.Journal of cancer research and clinical oncology · 2023Trial
- Construction of the prognostic model for small-cell lung cancer based on inflammatory markers: A real-world study of 612 cases with eastern cooperative oncology group performance score 0-1.Cancer medicine · 2023Trial
- A prognostic nomogram to predict survival in elderly patients with small-cell lung cancer: a large population-based cohort study and external validation.BMC cancer · 2022Trial
- Development and validation of a nomogram to predict cancer-specific survival in elderly patients with papillary thyroid carcinoma: a population-based study.BMC geriatrics · 2022Trial
- Prognostic nomogram to predict the overall survival of patients with early-onset colorectal cancer: a population-based analysis.International journal of colorectal disease · 2021Trial
- Development and external validation of an XGBoost-based prognostic model for small cell lung cancer with brain metastases.Translational cancer research · 2026Article
- Development and internal validation of dynamic nomograms for predicting recurrence and survival in patients with resected combined small cell lung cancer.Journal of thoracic disease · 2026Article
- Development and validation of a nomogram for predicting overall survival in small cell lung cancer: a multicenter analysis integrating multimodal therapy and molecular pathology.Translational lung cancer research · 2026Article
- Establishment of a mInternational journal of genomics · 2026Article
- Brief report: Artificial intelligence meets small cell lung cancer-integrating clinicopathological and wholeslide image data for prognostic prediction in SCLC.Frontiers in artificial intelligence · 2026Article
- A Prognostic Nomogram Combining Radiologic Emphysema and Clinical Parameters in Small Cell Lung Cancer.Cancer management and research · 2026Article
- Construction and Validation of a Predictive Model for Post-TACE Recurrence Risk in Hepatocellular Carcinoma: A Retrospective Cohort Study.Journal of hepatocellular carcinoma · 2026Article
- A nomogram predicting prognosis of extensive-stage small cell lung cancer patients receiving chemoradiotherapy.Radiation oncology (London, England) · 2025Article
- Development and Validation of a Clinlabomics-Based Nomogram for Predicting the Prognosis of Small Cell Lung Cancer in China: A Multicenter, Retrospective Cohort Study.Cancer medicine · 2025Observational
- A novel prognostic nomogram to predict survival of patients with esophageal squamous cell carcinoma after definitive chemoradiotherapy.Journal of thoracic disease · 2025Article
- Construction and validation of a predictive in-hospital mortality nomogram in patients with staphylococcus aureus bloodstream infection.Scientific reports · 2025Article
- PP2A Promotes the Symmetric Division of MUC1-Dominant Cancer Stem-Like Cells in Small Cell Lung Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Nomograms predicting cancer-specific survival and overall survival of advanced salivary gland malignancy patients: a study based on the SEER database.Discover oncology · 2025Article
- Development and validation of a CT-based radiomics nomogram for predicting progression-free survival in patients with small cell lung cancer.BMC medical imaging · 2025Article
- Development and validation of predictive models for distant metastasis and prognosis of gastroenteropancreatic neuroendocrine neoplasms.Scientific reports · 2025Article
73 more citing papers are in PubMed but not listed here.
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7 authors.
Funding
Abstract
introductionSCLC accounts for almost 15% of lung cancer cases in the United States. Nomogram prognostic models could greatly facilitate risk stratification and treatment planning, as well as more refined enrollment criteria for clinical trials. We developed and validated a new nomogram prognostic model for SCLC patients using a large SCLC patient cohort from the National Cancer Database (NCDB).
methodsClinical data for 24,680 SCLC patients diagnosed from 2004 to 2011 were used to develop the nomogram prognostic model. The model was then validated using an independent cohort of 9700 SCLC patients diagnosed from 2012 to 2013. The prognostic performance was evaluated using p value, concordance index and integrated area under the (time-dependent receiver operating characteristic) curve (AUC).
resultsThe following variables were contained in the final prognostic model: age, sex, race, ethnicity, Charlson/Deyo score, TNM stage (assigned according to the American Joint Committee on Cancer [AJCC] eighth edition), treatment type (combination of surgery, radiation therapy, and chemotherapy), and laterality. The model was validated in an independent testing group with a concordance index of 0.722 ± 0.004 and an integrated area under the curve of 0.79. The nomogram model has a significantly higher prognostic accuracy than previously developed models, including the AJCC eighth edition TNM-staging system. We implemented the proposed nomogram and four previously published nomograms in an online webserver.
conclusionsWe developed a nomogram prognostic model for SCLC patients, and validated the model using an independent patient cohort. The nomogram performs better than earlier models, including models using AJCC staging.
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