ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2019
Depressive Symptoms and Engagement in Human Immunodeficiency Virus Care Following Antiretroviral Therapy Initiation.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review of engagement in care and health care utilization among older adults living with HIV and non-communicable diseases.AIDS care · 2022Pooled it
- Global Systematic Review of Common Mental Health Disorders in Adults Living with HIV.Current HIV/AIDS reports · 2021Pooled it
- Effect of a WeChat-Based Intervention (Run4Love) on Depressive Symptoms Among People Living With HIV in China: A Randomized Controlled Trial.Journal of medical Internet research · 2020Trial
- Mechanisms and Effects of a WeChat-Based Intervention on Suicide Among People Living With HIV and Depression: Path Model Analysis of a Randomized Controlled Trial.Journal of medical Internet research · 2019Trial
- Culturally Tailored Materials for Smoking Cessation and HIV Care Adherence Among Hispanic Adults: Protocol for Content Development and Formative Evaluation.JMIR research protocols · 2026Article
- Life Instability and Its Effects on Psychosocial Syndemic Problems and HIV-Care Outcomes in People Living With HIV in Care in South Florida.Journal of acquired immune deficiency syndromes (1999) · 2026Article
- Article
- Sociodemographic and clinical factors associated with use of depression treatment among people with HIV in the United States: An electronic health records-based cohort study.Journal of affective disorders · 2025Article
- Early Outcomes of Mental Health Screening Integrated Into Routine HIV Care in Malawi.Global health, science and practice · 2024Article
- Conceptualizations of Mental Health Among Young Black Gay, Bisexual, and Other Men (YB-GBMSM) Who Have Sex With Men Who Are Living With HIV.AIDS education and prevention : official publication of the International Society for AIDS Education · 2024Article
- Prevalence of Mental Health Disorders and Their Associated Risk Factors Among People Living with HIV in Rwanda: A Cross-Sectional Study.AIDS and behavior · 2024Article
- Two decade trends in cardiovascular disease outcomes and cardiovascular risk factors among US veterans living with HIV.International journal of cardiology. Cardiovascular risk and prevention · 2022Article
- Burden and Correlates of Mental Health Symptoms Among Young Black Gay, Bisexual, and Other Men Who Have Sex with Men Engaged in HIV Care in Atlanta.AIDS and behavior · 2022Article
- A comprehensive analysis of excess depressive disorder in women and men living with HIV in France compared to the general population.Scientific reports · 2022Article
- The role of depression in secondary HIV transmission among people who inject drugs in Vietnam: A mathematical modeling analysis.PloS one · 2022Article
- A Prospective Study of Depressive Symptoms, Condomless Sex, and HIV Viral Load in HIV-Positive Female Sex Workers in Kenya.AIDS and behavior · 2021Article
- Depression and Viral Suppression Among Adults Living with HIV in Tanzania.AIDS and behavior · 2021Article
- Depression, antiretroviral therapy initiation, and HIV viral suppression among people who inject drugs in Vietnam.Journal of affective disorders · 2021Article
- HIV care cascade before and after hospitalization: impact of a multidisciplinary inpatient team in the US South.AIDS care · 2020Article
- Trajectories of Viral Suppression in People Living With HIV Receiving Coordinated Care: Differences by Comorbidities.Journal of acquired immune deficiency syndromes (1999) · 2020Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Background: The effect of depressive symptoms on progression through the human immunodeficiency virus (HIV) treatment cascade is poorly characterized. Methods: We included participants from the Centers for AIDS Research Network of Integrated Clinic Systems cohort who were antiretroviral therapy (ART) naive, had at least 1 viral load and HIV appointment measure after ART initiation, and a depressive symptom measure within 6 months of ART initiation. Recent depressive symptoms were measured using the Patient Health Questionnaire-9 (PHQ-9) and categorized using a validated cut point (PHQ-9 ≥10). We followed participants from ART initiation through the first of the following events: loss to follow-up (>12 months with no HIV appointment), death, administrative censoring (2011-2014), or 5 years of follow-up. We used log binomial models with generalized estimating equations to estimate associations between recent depressive symptoms and having a detectable viral load (≥75 copies/mL) or missing an HIV visit over time. Results: We included 1057 HIV-infected adults who contributed 2424 person-years. At ART initiation, 30% of participants reported depressive symptoms. In multivariable analysis, recent depressive symptoms increased the risk of having a detectable viral load (risk ratio [RR], 1.28; 95% confidence interval [CI], 1.07, 1.53) over time. The association between depressive symptoms and missing an HIV visit (RR, 1.20; 95% CI, 1.05, 1.36) moved to the null after adjustment for preexisting mental health conditions (RR, 1.00; 95% CI, 0.85, 1.18). Conclusions: Recent depressive symptoms are a risk factor for unsuppressed viral load, while preexisting mental health conditions may influence HIV appointment adherence.
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