Evidence map›Paper›PMID 29901472›Full record

SynthesisEye & contact lens2018

A Review of Current Concepts of the Etiology and Treatment of Myopia.

Jeffrey Cooper, Andrei V Tkatchenko

Registry-linked trialOpen access · hybridAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Eye & contact lens, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07653074 (Functional Vision and Quality of Life in a Modern Society - With Emphasis on Myopia and Cerebral Visual Impairment Among Youth), which is not on this map. Cited by 124 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
124citing papers in PubMed, 4 pooled it
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07653074 recruitingnot on this mapstarted 2024, after this paper: background citation

Functional Vision and Quality of Life in a Modern Society - With Emphasis on Myopia and Cerebral Visual Impairment Among Youth

Typeobservational_patient_registrySponsorRegion Örebro CountyRan2024 to 2029Enrolled300ConditionsMyopia, Quality of LifeArmsophthalmological examination
3 · Its place in the literature

Who cites it

124 citing papers in PubMed, 4 syntheses or guidelines pooled it, 295 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Orthokeratology lens-relatedThe Journal of international medical research · 2021
    Pooled it
  5. Accommodation response and spherical aberration during orthokeratology.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020
    Trial
  6. Bifocal & Atropine in Myopia Study: Baseline Data and Methods.Optometry and vision science : official publication of the American Academy of Optometry · 2019
    Trial
  7. Scleral Postn Drives Myopia via Promoting Myofibroblast Transdifferentiation.Investigative ophthalmology & visual science · 2026
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Impact of the COVID-19 pandemic lockdowns on manifest refraction in a young adult population: A large cohort study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Observational
  20. Article

64 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jeffrey CooperSUNY College of Optometry (J.C.D.), New York, NY; and Tkatchenko Department of Ophthalmology (A.V.T.), Edward S. Harkness Eye Institute, Columbia University Medical Center, New York, NY.
Andrei V Tkatchenko
Creative Commons · US

Funding

Instrumentation, Fabrication, and Design CoreP30EY019007 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Xin Zhang · 2010 to 2026
$12.9M
Genetics of refractive error development in the mouse modelR01EY023839 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI TKATCHENKO, ANDREI V. · 2014 to 2017
$1.6M
NEI NIH HHS P30 EY019007NEI NIH HHS R01 EY023839
6 · The paper itself

Abstract

Myopia occurs in more than 50% of the population in many industrialized countries and is expected to increase; complications associated with axial elongation from myopia are the sixth leading cause of blindness. Thus, understanding its etiology, epidemiology, and the results of various treatment regiments may modify current care and result in a reduction in morbidity from progressive myopia. This rapid increase cannot be explained by genetics alone. Current animal and human research demonstrates that myopia development is a result of the interplay between genetic and the environmental factors. The prevalence of myopia is higher in individuals whose both parents are myopic, suggesting that genetic factors are clearly involved in myopia development. At the same time, population studies suggest that development of myopia is associated with education and the amount time spent doing near work; hence, activities increase the exposure to optical blur. Recently, there has been an increase in efforts to slow the progression of myopia because of its relationship to the development of serious pathological conditions such as macular degeneration, retinal detachments, glaucoma, and cataracts. We reviewed meta-analysis and other of current treatments that include: atropine, progressive addition spectacle lenses, orthokeratology, and multifocal contact lenses.

Indexed as

AtropineContact LensesDisease ProgressionEyeglassesHumansMuscarinic AntagonistsMydriaticsMyopiaOrthokeratologic ProceduresRecreationAtropineMuscarinic AntagonistsMydriatics

Identifiers

PMID29901472
PMCPMC6023584
OpenAlexW2807926487

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.