Evidence map›Paper›PMID 29900958›Full record

ArticleArchives of rheumatology2016

A Systemic Lupus Erythematosus Patient With Febrile Neutropenia Developing After Intraocular Administration of Bevacizumab.

Hamdi Sözen, Gönen Mengi, Bülent Hüddam, Selmin Çaylak, Mehmet Deveer, Volkan Karakuş, Burak Ekrem Çitil

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Archives of rheumatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hamdi SözenDepartment of Infectious Disease, Medical Faculty of Muğla Sıtkı Koçman University, Muğla, Turkey.
Gönen MengiDepartment of Rheumatology, Medical Faculty of Muğla Sıtkı Koçman University, Muğla, Turkey.
Bülent HüddamDepartment of Nephrology, Medical Faculty of Muğla Sıtkı Koçman University, Muğla, Turkey.
Selmin ÇaylakDepartment of Infectious Disease, Medical Faculty of Muğla Sıtkı Koçman University, Muğla, Turkey.
Mehmet DeveerDepartment of Radiology, Medical Faculty of Muğla Sıtkı Koçman University, Muğla, Turkey.
Volkan KarakuşDepartment of Hematology, Medical Faculty of Muğla Sıtkı Koçman University, Muğla, Turkey.
Burak Ekrem ÇitilDepartment of Microbiology, Medical Faculty of Muğla Sıtkı Koçman University, Muğla, Turkey.
Muğla University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this article, we report a case with febrile neutropenia occurring after implementation of intraocular bevacizumab. A 60-year-old female patient who had received intravitreal bevacizumab applied to hospital for oral lesions accompanying fever and neutropenia. In spite of empiric antibiotherapy, patient's clinical condition did not improve. Her sputum culture yielded Stenotrophomonas maltophilia. Trimethoprim/ sulfamethoxazole and levofloxacin were commenced according to antibiogram. In immunologic evaluation, antinuclear antibodies and anti-double stranded deoxyribonucleic acid were positive as compatible with systemic lupus erythematosus. After proper antibiotic treatment, patient's clinical symptoms resolved. Development of severe neutropenia after procedures which are not expected to create systemic adverse effects should bring to mind underlying immunosuppressive diseases such as systemic lupus erythematosus.

Indexed as

Bevacizumabfebrile neutropeniaStenotrophomonas maltophiliasystemic lupus erythematosus

Identifiers

PMID29900958
PMCPMC5827835
OpenAlexW2344650345

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.