Evidence map›Paper›PMID 29900362›Full record

ArticleData in brief2018

Data on the localization of EGFP and 20α-hydroxysteroid dehydrogenase (20α-HSD) in the placenta and testes of transgenic mice.

Mi-Hyang Yoo, Chae-Won Park, Munkhzaya Byambaragchaa, Myung-Hwa Kang, Kwan-Sik Min

Open access · goldAbstract read
In one paragraph

Article in Data in brief, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mi-Hyang YooAnimal Biotechnology, Graduate School of Future Convergence Technology, Institute of Genetic Engineering, Dept. of Animal Life Science, Hankyong National University, Anseong 17579, Republic of Korea.
Chae-Won ParkAnimal Biotechnology, Graduate School of Future Convergence Technology, Institute of Genetic Engineering, Dept. of Animal Life Science, Hankyong National University, Anseong 17579, Republic of Korea.
Munkhzaya ByambaragchaaAnimal Biotechnology, Graduate School of Future Convergence Technology, Institute of Genetic Engineering, Dept. of Animal Life Science, Hankyong National University, Anseong 17579, Republic of Korea.
Myung-Hwa KangDepartment of Food Science & Nutrition, Hoseo University, Asan 31499, Republic of Korea.
Kwan-Sik MinAnimal Biotechnology, Graduate School of Future Convergence Technology, Institute of Genetic Engineering, Dept. of Animal Life Science, Hankyong National University, Anseong 17579, Republic of Korea.
Hankyong National University · KRHoseo University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to investigate the function of monkey 20α-hydroxysteroid dehydrogenase (20α-HSD), transgenic mice (tg) were produced, expressing enhanced green fluorescent protein (EGFP) under the control of the monkey 20α-HSD promoter. The expression levels and localization of EGFP and 20α-HSD were analyzed in immature testis and in placenta. In support of our recent publication, "Characterization of transgenic mice expressing EGFP under control of monkey 20α-hydroxysteroid dehydrogenase promoter" (Park et al., 2018) [1], it was important to characterize the function of EGFP and 20α-HSD in the ovarian luteal cells of tg mice. Here, the expression of EGFP and 20α-HSD in immature testis and placenta are presented. The expression level of EGFP and 20α-HSD were detected in the testes 1 week after birth, and increased dramatically at 8 weeks. Both of proteins strongly detected in the placenta on days 14, 16, and 18 of pregnancy. Immunohistochemical analysis revealed that EGFP was detected in the seminiferous epithelium and 20α-HSD was specifically localized in the seminiferous tubule at 8 weeks.

Indexed as

20α-HSD promoterPlacentaTestisTransgenic mice

Identifiers

PMID29900362
PMCPMC5997899
OpenAlexW2803893618

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.