Evidence map›Paper›PMID 29900113›Full record

ArticleEuPA open proteomics2016

Metabolite extraction for high-throughput FTICR-MS-based metabolomics of grapevine leaves.

Marisa Maia, Filipa Monteiro, Mónica Sebastiana, Ana Patrícia Marques, António E N Ferreira, Ana Ponces Freire, Carlos Cordeiro, Andreia Figueiredo, Marta Sousa Silva

Abstract read
In one paragraph

Article in EuPA open proteomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Pharmaceutics · 2019
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marisa MaiaBiosystems & Integrative Sciences Institute (BioISI), Science Faculty of Lisbon University, 1749-016 Lisbon, Portugal.
Filipa MonteiroBiosystems & Integrative Sciences Institute (BioISI), Science Faculty of Lisbon University, 1749-016 Lisbon, Portugal.
Mónica SebastianaBiosystems & Integrative Sciences Institute (BioISI), Science Faculty of Lisbon University, 1749-016 Lisbon, Portugal.
Ana Patrícia MarquesLaboratório de FTICR e Espectrometria de Massa Estrutural, Faculdade de Ciências da Universidade de Lisboa, Portugal.
António E N FerreiraLaboratório de FTICR e Espectrometria de Massa Estrutural, Faculdade de Ciências da Universidade de Lisboa, Portugal.
Ana Ponces FreireCentro de Química e Bioquímica, Faculdade de Ciências da Universidade de Lisboa, Portugal.
Carlos CordeiroLaboratório de FTICR e Espectrometria de Massa Estrutural, Faculdade de Ciências da Universidade de Lisboa, Portugal.
Andreia FigueiredoBiosystems & Integrative Sciences Institute (BioISI), Science Faculty of Lisbon University, 1749-016 Lisbon, Portugal.
Marta Sousa SilvaLaboratório de FTICR e Espectrometria de Massa Estrutural, Faculdade de Ciências da Universidade de Lisboa, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In metabolomics there is an ever-growing need for faster and more comprehensive analysis methods to cope with the increase of biological studies. Direct infusion Fourier-transform ion cyclotron-resonance mass spectrometry (DI-FTICR-MS) is used in non-targeted metabolomics to obtain high-resolution snapshots of the metabolic state of a system. In any metabolic profiling study, the establishment of an effective metabolite extraction protocol is paramount. We developed an improved metabolite extraction method, compatible with DI-FTICR-MS-based metabolomics, using grapevine leaves. This extraction protocol allowed the extraction of polar and non-polar compounds, covering all major classes found in plants and increasing metabolome coverage.

Indexed as

FTICR-MSMetabolomicsVitis vinifera

Identifiers

PMID29900113
PMCPMC5988515

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.