Evidence map›Paper›PMID 29900085›Full record

ArticleCureus2018

Target Volume Delineation Using Diffusion-weighted Imaging for MR-guided Radiotherapy: A Case Series of Laryngeal Cancer Validated by Pathology.

Hans Ligtenberg, Tim Schakel, Jan Willem Dankbaar, Lilian N Ruiter, Boris Peltenburg, Stefan M Willems, Nicolien Kasperts, Chris H J Terhaard, Cornelis P J Raaijmakers, Marielle E P Philippens

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Oncological outcome of vocal cord-only radiotherapy for cT1-T2 glottic laryngeal squamous cell carcinoma.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Article
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Hans LigtenbergDepartment of Radiotherapy, University Medical Center Utrecht, Utrecht, NLD.
Tim SchakelDepartment of Radiotherapy, University Medical Center Utrecht, Utrecht, NLD.
Jan Willem DankbaarDepartment of Radiology, University Medical Center Utrecht, Utrecht, NLD.
Lilian N RuiterDepartment of Pathology, University Medical Center Utrecht, Utrecht, NLD.
Boris PeltenburgDepartment of Radiotherapy, University Medical Center Utrecht, Utrecht, NLD.
Stefan M WillemsDepartment of Pathology, University Medical Center Utrecht, Utrecht, NLD.
Nicolien KaspertsDepartment of Radiotherapy, University Medical Center Utrecht, Utrecht, NLD.
Chris H J TerhaardDepartment of Radiotherapy, University Medical Center Utrecht, Utrecht, NLD.
Cornelis P J RaaijmakersDepartment of Radiotherapy, University Medical Center Utrecht, Utrecht, NLD.
Marielle E P PhilippensDepartment of Radiotherapy, University Medical Center Utrecht, Utrecht, NLD.
University Medical Center Utrecht · NLUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In radiotherapy treatment planning, tumor delineation based on diffusion-weighted imaging (DWI) by magnetic resonance imaging (MRI) is a promising technique. MR-only-based target definition becomes important with the recent development of MRI integrated radiotherapy treatment modalities. In this case series, DWI-based gross tumor volume (GTV) was validated using pathology and compared with a clinical GTV based on computed tomography (CT) imaging and MRI. This case series includes three patients with a laryngeal tumor. Prior to total laryngectomy (TLE), imaging was performed on CT and MRI, including a DWI scan. After TLE, the surgical specimen was processed and cut into 3-mm thick slices. The tumor was delineated on hematoxylin-eosin (HE) stained sections by a pathologist (tumor

Indexed as

dwigtvlarynxpathologyradiotherapytarget delineationvalidation

Identifiers

PMID29900085
PMCPMC5997430
OpenAlexW2797521644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.