ReviewJournal of the advanced practitioner in oncology2017
Managing Constipation in Adults With Cancer.
Review in Journal of the advanced practitioner in oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Trial
- Methylnaltrexone Treatment for Opioid-Induced Constipation in Patients with and without Cancer: Effect of Initial Dose.Journal of pain research · 2023Trial
- Experiences and coping strategies related to constipation among individuals with cancer: a qualitative study.BMC palliative care · 2026Article
- German Expert Consensus on Opioid-Induced Constipation (OIC): Recommendations and a Treatment Algorithm for Clinical Practice.Journal of clinical medicine · 2026Article
- Prophylactic laxative use for postoperative constipation in urological cancer: a real-world cohort study.World journal of urology · 2025Article
- Critical mistakes in managing chronic constipation in the older person and how to avoid them: A narrative review.Journal of general and family medicine · 2025Review
- Prediction of medication nonadherence in patients with lung cancer based on nomogram model construction.Medicine · 2025Observational
- Article
- Practical Management of Adverse Events Associated With FGFR Inhibitors for Cholangiocarcinoma for the Advanced Practice Provider.Journal of the advanced practitioner in oncology · 2024Review
- Prevalence of multimorbidity in survivors of 28 cancer sites: an English nationwide cross-sectional study.American journal of cancer research · 2024Article
- Impact of comorbid constipation on the survival of patients with heart failure: a multicenter, prospective cohort study conducted in Japan.Frontiers in cardiovascular medicine · 2024Article
- Maladaptive coping styles moderate the relationship between information on cancer treatment and psychosocial symptoms: an Italian multicenter study.Frontiers in psychology · 2024Article
- Review
- Cancer management from a chronic gastrointestinal function perspective.Clinical medicine (London, England) · 2023Review
- Expert consensus of management of adverse drug reactions with anaplastic lymphoma kinase tyrosine kinase inhibitors.ESMO open · 2023Review
- Impact of Patient Subgroups on the Efficacy and Safety of Methylnaltrexone for Opioid-Induced Constipation in Patients with Advanced Illness.Journal of pain research · 2023Article
- Subcutaneous Methylnaltrexone as Treatment for Opioid-Induced Constipation in Patients with Advanced Cancer and Noncancer Illnesses: A Post Hoc Analysis of Two Clinical Trials.Journal of pain research · 2023Article
- A pilot randomized placebo-controlled study on modified MaZiRenWan: a formulated Chinese medicine to relieve constipation for palliative cancer patients.Chinese medicine · 2022Article
- Constipation in Chemotherapy Patients: A Diagnostic Accuracy Study.Asian Pacific journal of cancer prevention : APJCP · 2021Article
- Physical Activity, Sitting Time, and Quality of Life among Breast and Gynaecology Cancer Survivors.Asian Pacific journal of cancer prevention : APJCP · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Constipation is common in individuals with cancer, occurring in almost 60% of patients overall. The incidence increases in patients with advanced disease, particularly in those receiving opioid analgesics or medications with anticholinergic properties. Constipation is not uniformly assessed and therefore not recognized and appropriately managed in many instances. This can increase patients' physical and psychological distress. Furthermore, there is scant research to support current management strategies for constipation. The objectives of this review are to explore the incidence of and risk factors for constipation in patients with cancer, to discuss the extent of the problem, to explore the nonpharmacologic and pharmacologic measures for constipation and fecal impaction, and to synthesize a laxative management. An extensive review of medical, pharmacy, and nursing literature was done to explore the physiology and pathogenesis of constipation; detail the mechanisms of action, onset of effect, approximate costs, and adverse effects of drugs for constipation; and condense clinical expert consensus recommendations for constipation, particularly in patients with cancer. Advanced practitioners (APs) and other clinicians play crucial roles in identifying individuals at risk for and experiencing constipation to help them use effective regimens, including over-the-counter laxatives, and perhaps adjunctive nondrug measures. Clinicians and patients must develop an agreed-upon language for identifying the severity and effects of constipation. In addition, both should understand which laxatives are most appropriate and which should be avoided for particular patients. Two prescription agents are also available, and understanding when they should be used is important for APs.
Identifiers
29900023PMC5995490What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.