Evidence map›Paper›PMID 29900011›Full record

ArticleNPJ vaccines2018

Adjuvant composition and delivery route shape immune response quality and protective efficacy of a recombinant vaccine for

Mayuresh M Abhyankar, Mark T Orr, Susan Lin, Mohammed O Suraju, Adrian Simpson, Molly Blust, Tiep Pham, Jeffrey A Guderian, Mark A Tomai, James Elvecrog and 3 more

Open access · goldAbstract read
In one paragraph

Article in NPJ vaccines, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Immunogenicity and safety of anHuman vaccines & immunotherapeutics · 2024
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Membranes · 2022
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Investigating the Efficiency of Recombinant FliC-LoadedIranian journal of public health · 2021
    Article
  14. Review
  15. Optimizing a Multi-Component IntranasalFrontiers in immunology · 2021
    Article
  16. Article
  17. New horizons in adjuvants for vaccine development.Current opinion in immunology · 2020
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Mayuresh M Abhyankar1Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia Health System, Charlottesville, VA USA.
Mark T Orr2IDRI, 1616 Eastlake Ave E, Seattle, WA USA.
Susan Lin2IDRI, 1616 Eastlake Ave E, Seattle, WA USA.
Mohammed O Suraju1Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia Health System, Charlottesville, VA USA.
Adrian Simpson2IDRI, 1616 Eastlake Ave E, Seattle, WA USA.
Molly Blust2IDRI, 1616 Eastlake Ave E, Seattle, WA USA.
Tiep Pham2IDRI, 1616 Eastlake Ave E, Seattle, WA USA.
Jeffrey A Guderian2IDRI, 1616 Eastlake Ave E, Seattle, WA USA.
Mark A Tomai3M Drug Delivery Systems, 3M Center, 275-3E-10, St. Paul, MN USA.
James Elvecrog3M Drug Delivery Systems, 3M Center, 275-3E-10, St. Paul, MN USA.
Karl Pedersen5TECHLAB, Inc., 2001 Kraft Drive, Blacksburg, VA USA.
William A Petri1Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia Health System, Charlottesville, VA USA.
Christopher B Fox2IDRI, 1616 Eastlake Ave E, Seattle, WA USA.ORCID 0000-0002-4644-2619
Infectious Disease Research Institute · USUniversity of Virginia Health System · USKindeva Drug Delivery (United States) · USTechLab (United States) · US

Funding

FIELD STUDIES OF IMMUNITY TO AMEBIASIS IN BANGLADESHR01AI043596 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI CAROL A GILCHRIST, William A Petri · 1998 to 2026
$7.7M
Alum-absorbed subunit vaccine to prevent intestinal amebiasisR43AI085938 · NIAID · TECHLAB, INC. · PI LYERLY, DAVID M. · 2011 to 2012
$600k
Nanoformulation of Synergistic TLR Ligands to Enhance Amebiasis Vaccine EfficacyR21AI109118 · NIAID · ACCESS TO ADVANCED HEALTH INSTITUTE · PI FOX, CHRISTOPHER B · 2014 to 2015
$445k
NIAID NIH HHS R01 AI043596NIAID NIH HHS R21 AI109118NIAID NIH HHS R43 AI085938
6 · The paper itself

Abstract

Amebiasis caused by

Identifiers

PMID29900011
PMCPMC5988657
OpenAlexW2807129261

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.