Evidence map›Paper›PMID 29900003›Full record

ArticleMultiple sclerosis journal - experimental, translational and clinical

Novel computer-based testing shows multi-domain cognitive dysfunction in patients with multiple sclerosis.

Andrew D Smith, Charles Duffy, Andrew D Goodman

Abstract read
In one paragraph

Article in Multiple sclerosis journal - experimental, translational and clinical. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Andrew D SmithDepartment of Neurology, Dartmouth-Hitchcock Medical Center, Geisel School of Medicine Dartmouth College, USA.ORCID 0000-0003-3002-222X
Charles DuffyDepartment of Neurology, University of Rochester Medical Center, USA.
Andrew D GoodmanDepartment of Neurology, University of Rochester Medical Center, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough cognitive dysfunction is a leading cause of disability and poor quality of life in patients with multiple sclerosis (MS), it is infrequently tested in routine clinical evaluation. Development of a cognitive testing paradigm that captured MS-related cognitive dysfunction and could be obtained in a routine clinical setting may increase surveillance and recognition of cognitive dysfunction.

objectivesThis was a pilot study to determine if

resultsSignificant differences were found between MS and HC on SDMT, PASAT, and

conclusion

Indexed as

cognitioncognitive testingCognivuecomputer-based cognitive testingMultiple sclerosis (MS)

Identifiers

PMID29900003
PMCPMC5993067

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.