Evidence map›Paper›PMID 29899995›Full record

ArticleHuman genome variation2018

High-resolution melting analysis coupled with next-generation sequencing as a simple tool for the identification of a novel somatic BRCA2 variant: a case report.

Alessandra Costella, Rossella De Leo, Donatella Guarino, Marco D'Indinosante, Paola Concolino, Giorgia Mazzuccato, Andrea Urbani, Giovanni Scambia, Ettore Capoluongo, Anna Fagotti and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Human genome variation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Alessandra Costella1Area Diagnostica di Laboratorio IRCCS, Rome, Italy.
Rossella De LeoDepartment of Obstetrics and Gynecology, Division of Gynecologic Oncology, Rome, Italy.
Donatella Guarino1Area Diagnostica di Laboratorio IRCCS, Rome, Italy.
Marco D'IndinosanteDepartment of Obstetrics and Gynecology, Division of Gynecologic Oncology, Rome, Italy.
Paola Concolino1Area Diagnostica di Laboratorio IRCCS, Rome, Italy.
Giorgia Mazzuccato1Area Diagnostica di Laboratorio IRCCS, Rome, Italy.
Andrea Urbani1Area Diagnostica di Laboratorio IRCCS, Rome, Italy.
Giovanni ScambiaDepartment of Obstetrics and Gynecology, Division of Gynecologic Oncology, Rome, Italy.
Ettore CapoluongoInstitute of Biochemistry and Clinical Biochemistry, Teaching and Research Hospital "Agostino Gemelli" Foundation, Rome, Italy.
Anna FagottiDepartment of Obstetrics and Gynecology, Division of Gynecologic Oncology, Rome, Italy.
Angelo Minucci1Area Diagnostica di Laboratorio IRCCS, Rome, Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · ITAgostino Gemelli University Polyclinic · ITIstituto Dermopatico dell'Immacolata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a 72-year-old woman with no associated personal or family history of breast and/or ovarian cancers, we identified a novel somatic pathogenic

Indexed as

High-resolution melting analysisnext-generation sequencingnovel somatic BRCA2 variant

Identifiers

PMID29899995
PMCPMC5993729
OpenAlexW2805317696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.