Evidence map›Paper›PMID 29899946›Full record

ArticleChemical science2016

Location dependent coordination chemistry and MRI relaxivity, in

Matthew R Berwick, Louise N Slope, Caitlin F Smith, Siobhan M King, Sarah L Newton, Richard B Gillis, Gary G Adams, Arthur J Rowe, Stephen E Harding, Melanie M Britton and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Design of the elusive proteinaceous oxygen donor copper site suggests a promising future for copper for MRI contrast agents.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  6. Article
  7. De novo metalloprotein design.Nature reviews. Chemistry · 2022
    Article
  8. Article
  9. Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  10. Quarterly reviews of biophysics · 2020
    Review
  11. Insulin Hexamer-Caged Gadolinium Ion as MRI Contrast-o-phore.Chemistry (Weinheim an der Bergstrasse, Germany) · 2018
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Matthew R BerwickSchool of Chemistry , University of Birmingham , Edgbaston , B15 2TT , UK . Email: a.f.a.peacock@bham.ac.uk.
Louise N SlopeSchool of Chemistry , University of Birmingham , Edgbaston , B15 2TT , UK . Email: a.f.a.peacock@bham.ac.uk.
Caitlin F SmithSchool of Chemistry , University of Birmingham , Edgbaston , B15 2TT , UK . Email: a.f.a.peacock@bham.ac.uk.
Siobhan M KingSchool of Chemistry , University of Birmingham , Edgbaston , B15 2TT , UK . Email: a.f.a.peacock@bham.ac.uk.
Sarah L NewtonSchool of Chemistry , University of Birmingham , Edgbaston , B15 2TT , UK . Email: a.f.a.peacock@bham.ac.uk.
Richard B GillisNational Centre for Macromolecular Hydrodynamics , School of Biosciences , University of Nottingham , Sutton Bonington , LE12 5RD , UK.
Gary G AdamsNational Centre for Macromolecular Hydrodynamics , School of Biosciences , University of Nottingham , Sutton Bonington , LE12 5RD , UK.
Arthur J RoweNational Centre for Macromolecular Hydrodynamics , School of Biosciences , University of Nottingham , Sutton Bonington , LE12 5RD , UK.
Stephen E HardingNational Centre for Macromolecular Hydrodynamics , School of Biosciences , University of Nottingham , Sutton Bonington , LE12 5RD , UK.
Melanie M BrittonSchool of Chemistry , University of Birmingham , Edgbaston , B15 2TT , UK . Email: a.f.a.peacock@bham.ac.uk.
Anna F A PeacockSchool of Chemistry , University of Birmingham , Edgbaston , B15 2TT , UK . Email: a.f.a.peacock@bham.ac.uk.
The Edgbaston Hospital · GBCzech Academy of Sciences, Institute of Hydrodynamics · CZUniversity of Birmingham · GBQueen's Medical Centre · GBUniversity of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, we establish for the first time the design principles for lanthanide coordination within coiled coils, and the important consequences of binding site translation. By interrogating design requirements and by systematically translating binding site residues, one can influence coiled coil stability and more importantly, the lanthanide coordination chemistry. A 10 Å binding site translation along a coiled coil, transforms a coordinatively saturated Tb(Asp)

Identifiers

PMID29899946
PMCPMC5968752
OpenAlexW2198334770

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.