Evidence map›Paper›PMID 29899852›Full record

ArticleOncotarget2018

Concomitant driver mutations in advanced

Jan Nyrop Jakobsen, Eric Santoni-Rugiu, Morten Grauslund, Linea Melchior, Jens Benn Sørensen

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 40 citations in OpenAlex.

  1. Novel Co-Occurrence of GermlineInternational journal of molecular sciences · 2026
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  4. ALK-tyrosine kinase inhibitor intrinsic resistance due toTranslational lung cancer research · 2024
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  5. Review
  6. Observational
  7. Article
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  9. Observational
  10. Clinical outcome of Brazilian patients with non-small cell lung cancer in early stage harboring rare mutations in epidermal growth factor receptor.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2023
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
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  17. Review
  18. Article
  19. Tumor Analyses Reveal Squamous Transformation and Off-Target Alterations As Early Resistance Mechanisms to First-line Osimertinib inClinical cancer research : an official journal of the American Association for Cancer Research · 2020
    Article
  20. Changing ALK-TKI-Resistance Mechanisms in Rebiopsies ofInternational journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jan Nyrop JakobsenDepartment of Oncology, Copenhagen University Hospital/Rigshospitalet, Copenhagen, Denmark.
Eric Santoni-RugiuDepartment of Pathology, Copenhagen University Hospital/Rigshospitalet, Copenhagen, Denmark.
Morten GrauslundDepartment of Pathology, Copenhagen University Hospital/Rigshospitalet, Copenhagen, Denmark.
Linea MelchiorDepartment of Pathology, Copenhagen University Hospital/Rigshospitalet, Copenhagen, Denmark.
Jens Benn SørensenDepartment of Oncology, Copenhagen University Hospital/Rigshospitalet, Copenhagen, Denmark.
Copenhagen University Hospital · DKRigshospitalet · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with

methodsFive hundred and fourteen consecutive patients with NSCLC of all stages were tested for

resultsThirty-six patients (7%) had

conclusionCo-mutations in other cancer-driver genes (oncogenes or tumor suppressor genes) were frequent in

Indexed as

EGFRerlotinibmutationNSCLCtarceva

Identifiers

PMID29899852
PMCPMC5995236
OpenAlexW2804482009

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.