Evidence map›Paper›PMID 29899827›Full record

ArticleOncotarget2018

Platelet activation parameters and platelet-leucocyte-conjugate formation in glioblastoma multiforme patients.

Sascha Marx, Maximilian Splittstöhser, Frederik Kinnen, Eileen Moritz, Christy Joseph, Sebastian Paul, Heiko Paland, Carolin Seifert, Madlen Marx, Andreas Böhm and 7 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Sascha MarxDepartment of Neurosurgery, University Medicine Greifswald, Greifswald, Germany.
Maximilian SplittstöhserDepartment of Neurosurgery, University Medicine Greifswald, Greifswald, Germany.
Frederik KinnenDepartment of Neurosurgery, University Medicine Greifswald, Greifswald, Germany.
Eileen MoritzDepartment of Pharmacology, Center of Drug Absorption and Transport (C_DAT), University of Medicine Greifswald, Greifswald, Germany.
Christy JosephDepartment of Pharmacology, Center of Drug Absorption and Transport (C_DAT), University of Medicine Greifswald, Greifswald, Germany.
Sebastian PaulDepartment of Ophthalmology, University Medicine Greifswald, Greifswald, Germany.
Heiko PalandDepartment of Neurosurgery, University Medicine Greifswald, Greifswald, Germany.
Carolin SeifertDepartment of Neurosurgery, University Medicine Greifswald, Greifswald, Germany.
Madlen MarxDepartment of Paediatric Oncology and Haematology, University Medicine Greifswald, Greifswald, Germany.
Andreas BöhmDepartment of Pharmacology, Center of Drug Absorption and Transport (C_DAT), University of Medicine Greifswald, Greifswald, Germany.
Edzard SchwedhelmInstitute of Clinical Pharmacology and Toxicology, University Medical Center, Hamburg, Germany.
Kerstin HolzerInstitute of Pathology, University Medicine Greifswald, Greifswald, Germany.
Stephan SingerInstitute of Pathology, University Medicine Greifswald, Greifswald, Germany.
Christoph A RitterClinical Pharmacy, Institute of Pharmacy, University of Greifswald, Greifswald, Germany.
Sandra Bien-MöllerDepartment of Neurosurgery, University Medicine Greifswald, Greifswald, Germany.
Henry W S SchroederDepartment of Neurosurgery, University Medicine Greifswald, Greifswald, Germany.
Bernhard H RauchDepartment of Pharmacology, Center of Drug Absorption and Transport (C_DAT), University of Medicine Greifswald, Greifswald, Germany.
Universitätsmedizin Greifswald · DEUniversität Greifswald · DEUniversity Medical Center Hamburg-Eppendorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with glioblastoma multiforme (GBM) suffer from an increased incidence of vascular thrombotic events. However, key influencing factors of the primary hemostasis have not been characterized in GBM patients to date. Thus, the present study determines the activation level of circulating platelets in GBM patients,

Indexed as

glioblastoma multiformeplatelet activationP-selectinPSGL-1sphingosine-1-phosphat

Identifiers

PMID29899827
PMCPMC5995223
OpenAlexW2804367219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.