Evidence map›Paper›PMID 29899724›Full record

ArticleFrontiers in neurology2018

Gait Stability Has Phase-Dependent Dual-Task Costs in Parkinson's Disease.

Peter C Fino, Martina Mancini, Carolin Curtze, John G Nutt, Fay B Horak

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 30 citations in OpenAlex.

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  12. The relationship between attention and static balance disturbance in patients with Parkinson's disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Article
  13. Evaluation of movement and brain activity.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2021
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Phase-Dependent Effects of Closed-Loop Tactile Feedback on Gait Stability in Parkinson's Disease.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2020
    Article
  19. Speeding Up Gait in Parkinson's Disease.Journal of Parkinson's disease · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Peter C FinoDepartment of Neurology, Oregon Health & Science University, Portland, OR, United States.
Martina ManciniDepartment of Neurology, Oregon Health & Science University, Portland, OR, United States.
Carolin CurtzeDepartment of Neurology, Oregon Health & Science University, Portland, OR, United States.
John G NuttDepartment of Neurology, Oregon Health & Science University, Portland, OR, United States.
Fay B HorakDepartment of Neurology, Oregon Health & Science University, Portland, OR, United States.
Oregon Health & Science University · USVA Portland Health Care System · US

Funding

Oregon Clinical and Translational Research Institute - The National COVID Cohort Collaborative (N3C)UL1TR002369 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Cynthia D Morris, Christopher G. Slatore · 2017 to 2026
$78.4M
PERIPHERAL AND CENTRAL POSTURAL DISORDERS IN THE ELDERLYR01AG006457 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI HORAK, FAY BAHLING · 1986 to 2018
$5.2M
Body-Worn Sensors to Characterize & Treat Freezing of Gait in Parkinson's DiseaseR00HD078492 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI MANCINI, MARTINA · 2016 to 2018
$701k
NCATS NIH HHS UL1 TR002369NIA NIH HHS R01 AG006457NICHD NIH HHS R00 HD078492
6 · The paper itself

Abstract

Dual-task (DT) paradigms have been used in gait research to assess the automaticity of locomotion, particularly in people with Parkinson's disease (PD). In people with PD, reliance on cortical control during walking leads to greater interference between cognitive and locomotor tasks. Yet, recent studies have suggested that even healthy gait requires cognitive control, and that these cognitive contributions occur at specific phases of the gait cycle. Here, we examined whether changes in gait stability, elicited by simultaneous cognitive DTs, were specific to certain phases of the gait cycle in people with PD. Phase-dependent local dynamic stability (LDS) was calculated for 95 subjects with PD and 50 healthy control subjects during both single task and DT gait at phases corresponding to (1) heel contact-weight transfer, (2) toe-off-early swing, and (3) single-support-mid swing. PD-related DT interference was evident only for the duration of late swing and LDS during the heel contact-weight transfer phase of gait. No PD-related DT costs were found in other traditional spatiotemporal gait parameters. These results suggest that PD-related DT interference occurs only during times where cortical activity is needed for planning and postural adjustments. These results challenge our understanding of DT costs while walking, particularly in people with PD, and encourage researchers to re-evaluate traditional concepts of DT interference.

Indexed as

cognitive dual-taskdynamic postural controllocal dynamic stabilitylocomotionlyapunov exponents

Identifiers

PMID29899724
PMCPMC5988879
OpenAlexW2801450284

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.