Evidence map›Paper›PMID 29899699›Full record

ArticleFrontiers in pharmacology2018

Effects of Simultaneous Downregulation of PHD1 and Keap1 on Prevention and Reversal of Liver Fibrosis in Mice.

Jing Liu, Wencai Li, Manoj H Limbu, Yiping Li, Zhi Wang, Zhengyuan Cheng, Xiaoyi Zhang, Pingsheng Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. PHD1-3 oxygen sensors in vivo-lessons learned from gene deletions.Pflugers Archiv : European journal of physiology · 2024
    Review
  2. Article
  3. Extracellular histones stimulate collagen expressionWorld journal of gastroenterology · 2020
    Article
  4. Hypoxia and HIF Signaling: One Axis with Divergent Effects.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jing LiuDepartment of Pathology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Wencai LiDepartment of Pathology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Manoj H LimbuDepartment of Pathology and Pathophysiology, School of Medicine, Southeast University, Nanjing, China.
Yiping LiDepartment of Pathology and Pathophysiology, School of Medicine, Southeast University, Nanjing, China.
Zhi WangDepartment of Pathology and Pathophysiology, School of Medicine, Southeast University, Nanjing, China.
Zhengyuan ChengDepartment of Pathology and Pathophysiology, School of Medicine, Southeast University, Nanjing, China.
Xiaoyi ZhangDepartment of Pathology and Pathophysiology, School of Medicine, Southeast University, Nanjing, China.
Pingsheng ChenDepartment of Pathology and Pathophysiology, School of Medicine, Southeast University, Nanjing, China.
Southeast University · CNFirst Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

hepatocyteshypoxiaKeap1liver fibrosisoxidative stressPHD1

Identifiers

PMID29899699
PMCPMC5988854
OpenAlexW2805670949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.