Site-Specific Protein PEGylation: Application to Cysteine Analogs of Recombinant Human Granulocyte Colony-Stimulating Factor.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

1. Characterization of a Long-Acting Site-Specific PEGylated Murine GM-CSF Analog and Analysis of Its Hematopoietic Properties in Normal and Cyclophosphamide-Treated Neutropenic Rats.The protein journal · 2020
   Article
2. Development of Site-Specific PEGylated Granulocyte Colony Stimulating Factor With Prolonged Biological Activity.Frontiers in bioengineering and biotechnology · 2020
   Article
3. PEGylated G-CSF (BBT-015), GM-CSF (BBT-007), and IL-11 (BBT-059) analogs enhance survival and hematopoietic cell recovery in a mouse model of the hematopoietic syndrome of the acute radiation syndrome.Health physics · 2014
   Article
4. Hematopoietic properties of granulocyte colony-stimulating factor/immunoglobulin (G-CSF/IgG-Fc) fusion proteins in normal and neutropenic rodents.PloS one · 2014
   Article
5. Site-specific PEGylation enhances the pharmacokinetic properties and antitumor activity of interferon beta-1b.Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2013
   Article
6. PASylation: a biological alternative to PEGylation for extending the plasma half-life of pharmaceutically active proteins.Protein engineering, design & selection : PEDS · 2013
   Article
7. Of [Hamsters] and men: a new perspective on host cell proteins.Human vaccines & immunotherapeutics · 2012
   Article
8. Improving the stability of the EC1 domain of E-cadherin by thiol alkylation of the cysteine residue.International journal of pharmaceutics · 2012
   Article
9. The role of thiols and disulfides on protein stability.Current protein & peptide science · 2009
   Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

5 authors at 1 institution in 1 country.

Funding

Abstract

PubMed holds no abstract for this paper.