Evidence map›Paper›PMID 29899351›Full record

ArticleScientific reports2018

Factors influencing the induction of high affinity antibodies to Plasmodium falciparum merozoite antigens and how affinity changes over time.

Muyideen K Tijani, Sreenivasulu B Reddy, Christine Langer, James G Beeson, Mats Wahlgren, Roseangela I Nwuba, Kristina E M Persson

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Development of high affinity antibodies toFrontiers in immunology · 2025
    Article
  4. Parasite epidemiology and control · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Parasite-Related Genetic and Epigenetic Aspects and Host Factors InfluencingFrontiers in cellular and infection microbiology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Muyideen K TijaniCellular Parasitology Programme, Cell Biology and Genetics Unit, Department of Zoology, University of Ibadan, Ibadan, Nigeria.
Sreenivasulu B ReddyDepartment of Microbiology, Tumor and Cell Biology (MTC), Karolinska Institutet, Stockholm, Sweden.
Christine LangerThe Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia.
James G BeesonThe Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia.
Mats WahlgrenDepartment of Microbiology, Tumor and Cell Biology (MTC), Karolinska Institutet, Stockholm, Sweden.
Roseangela I NwubaCellular Parasitology Programme, Cell Biology and Genetics Unit, Department of Zoology, University of Ibadan, Ibadan, Nigeria.
Kristina E M PerssonDepartment of Microbiology, Tumor and Cell Biology (MTC), Karolinska Institutet, Stockholm, Sweden. kristina.persson@med.lu.se.
Burnet Institute · AUKarolinska Institutet · SEUniversity of Ibadan · NGSkåne University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the functional characteristics of naturally acquired antibodies against P. falciparum merozoite antigens is crucial for determining the protective functions of antibodies. Affinity (measured as k

Indexed as

Adaptive ImmunityAdolescentAdultAntibodies, ProtozoanAntibody AffinityAntigens, ProtozoanChildChild, PreschoolHumansImmunoglobulin GLongitudinal StudiesMalaria, FalciparumMerozoitesNigeriaPlasmodium falciparumSurface Plasmon ResonanceAntibodies, ProtozoanAntigens, ProtozoanImmunoglobulin G

Identifiers

PMID29899351
PMCPMC5998021
OpenAlexW2807384356

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.