Evidence map›Paper›PMID 29899303›Full record

ArticleFoods (Basel, Switzerland)2018

Optimizing Extraction Conditions of Free and Bound Phenolic Compounds from Rice By-Products and Their Antioxidant Effects.

Maria Irakli, Fotis Kleisiaris, Kalliopi Kadoglidou, Dimitrios Katsantonis

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 69 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Optimization of phenolic extraction method andFood hydrocolloids for health · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Valorization of Rice Husk (Foods (Basel, Switzerland) · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Recovery of Polyphenols from Brewer's Spent Grains.Antioxidants (Basel, Switzerland) · 2019
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Maria IrakliHellenic Agricultural Organization "Demeter", Institute of Plant Breeding & Genetic Resources, P.O. Box 60411, GR-57001 Thermi-Thessaloniki, Greece. irakli@cerealinstitute.gr.
Fotis KleisiarisHellenic Agricultural Organization "Demeter", Institute of Plant Breeding & Genetic Resources, P.O. Box 60411, GR-57001 Thermi-Thessaloniki, Greece. cerealtech@cerealinstitute.gr.
Kalliopi KadoglidouHellenic Agricultural Organization "Demeter", Institute of Plant Breeding & Genetic Resources, P.O. Box 60411, GR-57001 Thermi-Thessaloniki, Greece. kadoglidou@ipgrb.gr.
Dimitrios KatsantonisHellenic Agricultural Organization "Demeter", Institute of Plant Breeding & Genetic Resources, P.O. Box 60411, GR-57001 Thermi-Thessaloniki, Greece. dikatsa@cerealinstitute.gr.
Federation of Greek Mariculture · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rice by-products are extensively abundant agricultural wastes from the rice industry. This study was designed to optimize experimental conditions for maximum recovery of free and bound phenolic compounds from rice by-products. Optimized conditions were determined using response surface methodology based on total phenolic content (TPC), ABTS radical scavenging activity and ferric reducing power (FRAP). A Box-Behnken design was used to investigate the effects of ethanol concentration, extraction time and temperature, and NaOH concentration, hydrolysis time and temperature for free and bound fractions, respectively. The optimal conditions for the free phenolics were 41⁻56%, 40 °C, 10 min, whereas for bound phenolics were 2.5⁻3.6 M, 80 °C, 120 min. Under these conditions free TPC, ABTS and FRAP values in the bran were approximately 2-times higher than in the husk. However, bound TPC and FRAP values in the husk were 1.9- and 1.2-times higher than those in the bran, respectively, while bran fraction observed the highest ABTS value. Ferulic acid was most evident in the bran, whereas

Indexed as

alkaline hydrolysisantioxidant activityfree extractionoptimization extractionphenolicsresponse surface methodologyrice branrice husk

Identifiers

PMID29899303
PMCPMC6024898
OpenAlexW2808486902

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.