Evidence map›Paper›PMID 29899269›Full record

ArticleViruses2018

A Simple and Robust Approach for Evaluation of Antivirals Using a Recombinant Influenza Virus Expressing

Ping Li, Qinghua Cui, Lin Wang, Xiujuan Zhao, Yingying Zhang, Balaji Manicassamy, Yong Yang, Lijun Rong, Ruikun Du

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Screening for Anti-Influenza Actives of Prefractionated Traditional Chinese Medicines.Evidence-based complementary and alternative medicine : eCAM · 2020
    Article
  8. Article
  9. Article
  10. Article
  11. Qualitative and Quantitative Analysis for the Chemical Constituents ofEvidence-based complementary and alternative medicine : eCAM · 2019
    Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Ping LiCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China. liping9309@163.com.
Qinghua CuiCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China. user753951@163.com.
Lin WangCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China. lynn942@163.com.
Xiujuan ZhaoCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China. xiujuan95@163.com.
Yingying ZhangShandong Provincial Collaborative Innovation Center for Antiviral Traditional Chinese Medicine, Jinan 250355, China. zyy8965@163.com.
Balaji ManicassamyDepartment of Microbiology, University of Chicago, Chicago, IL 60637, USA. bmanicassamy@bsd.uchicago.edu.
Yong YangShandong Provincial Collaborative Innovation Center for Antiviral Traditional Chinese Medicine, Jinan 250355, China. yy7204@163.com.
Lijun RongDepartment of Microbiology and Immunology, College of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA. lijun@uic.edu.
Ruikun DuCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China. duzi857@163.com.
Shandong University of Traditional Chinese Medicine · CNIllinois College · USUniversity of Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influenza A virus (IAV) causes seasonal epidemics and occasional but devastating pandemics, which are major public health concerns. Because the effectiveness of seasonal vaccines is highly variable and the currently available drugs are limited in their efficacy because of the emergence of drug resistance, there is an urgent need to develop novel antivirals. In this study, we characterized a recombinant IAV-carrying

Indexed as

AnimalsAntiviral AgentsDogsDrug Evaluation, PreclinicalGenes, ReporterHEK293 CellsHumansInfluenza A virusLuciferasesLungMadin Darby Canine Kidney CellsMiceOrthomyxoviridae InfectionsStaining and LabelingTreatment OutcomeAntiviral AgentsLuciferasesantiviralGaussia luciferaseinfluenza A virustherapeutics

Identifiers

PMID29899269
PMCPMC6024319
OpenAlexW2808016044

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.