Evidence map›Paper›PMID 29899148›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Auxin methylation is required for differential growth in

Mohamad Abbas, Jorge Hernández-García, Stephan Pollmann, Sophia L Samodelov, Martina Kolb, Jiří Friml, Ulrich Z Hammes, Matias D Zurbriggen, Miguel A Blázquez, David Alabadí

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
8.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Mechanisms of auxin action in plant growth and development.Nature reviews. Molecular cell biology · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Spatial regulation of plant hormone action.Journal of experimental botany · 2023
    Review
  10. The Aqueous Extract ofPlants (Basel, Switzerland) · 2023
    Article
  11. Review
  12. Chemical inhibition of the auxin inactivation pathway uncovers the roles of metabolic turnover in auxin homeostasis.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  13. Auxin methylation byProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  14. Life (Basel, Switzerland) · 2022
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Auxin Metabolism in Plants.Cold Spring Harbor perspectives in biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Mohamad AbbasInstituto de Biología Molecular y Celular de Plantas, Consejo Superior de Investigaciones Científicas-Universidad Politécnica de Valencia, 46022 Valencia, Spain.
Jorge Hernández-GarcíaInstituto de Biología Molecular y Celular de Plantas, Consejo Superior de Investigaciones Científicas-Universidad Politécnica de Valencia, 46022 Valencia, Spain.ORCID 0000-0003-2526-8639
Stephan PollmannCentro de Biotecnología y Genómica de Plantas, Universidad Politécnica de Madrid-Instituto Nacional de Investigación y Tecnología Agraria y Alimentación, 28223 Pozuelo de Alarcón, Spain.
Sophia L SamodelovInstitute of Synthetic Biology and Cluster of Excellence in Plant Sciences, University of Düsseldorf, 40225 Düsseldorf, Germany.
Martina KolbDepartment of Cell Biology and Biochemistry, Regensburg University, 93053 Regensburg, Germany.
Jiří FrimlInstitute of Science and Technology Austria, 3400 Klosterneuburg, Austria.
Ulrich Z HammesDepartment of Cell Biology and Biochemistry, Regensburg University, 93053 Regensburg, Germany.
Matias D ZurbriggenInstitute of Synthetic Biology and Cluster of Excellence in Plant Sciences, University of Düsseldorf, 40225 Düsseldorf, Germany.
Miguel A BlázquezInstituto de Biología Molecular y Celular de Plantas, Consejo Superior de Investigaciones Científicas-Universidad Politécnica de Valencia, 46022 Valencia, Spain; mblazquez@ibmcp.upv.es.ORCID 0000-0001-5743-0448
David AlabadíInstituto de Biología Molecular y Celular de Plantas, Consejo Superior de Investigaciones Científicas-Universidad Politécnica de Valencia, 46022 Valencia, Spain.
Consejo Superior de Investigaciones Científicas · ESUniversity of Regensburg · DECluster of Excellence on Plant Sciences · DEInstitute of Science and Technology Austria · ATInstituto Nacional de Investigación y Tecnología Agraria y Alimentaria · ESUniversity of Freiburg · DE

Funding

European Research Council 282300
6 · The paper itself

Abstract

Asymmetric auxin distribution is instrumental for the differential growth that causes organ bending on tropic stimuli and curvatures during plant development. Local differences in auxin concentrations are achieved mainly by polarized cellular distribution of PIN auxin transporters, but whether other mechanisms involving auxin homeostasis are also relevant for the formation of auxin gradients is not clear. Here we show that auxin methylation is required for asymmetric auxin distribution across the hypocotyl, particularly during its response to gravity. We found that loss-of-function mutants in

Indexed as

ArabidopsisArabidopsis ProteinsGene Expression Regulation, PlantHypocotylIndoleacetic AcidsMethylationMethyltransferasesMutationArabidopsis ProteinsIAMT1 protein, ArabidopsisIndoleacetic AcidsMethyltransferasesPIN3 protein, Arabidopsisauxin metabolismgravitropismhomeostasishormone regulation

Identifiers

PMID29899148
PMCPMC6042151
OpenAlexW2808165554

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.