Evidence map›Paper›PMID 29899118›Full record

ArticleThe Journal of biological chemistry2018

Endocytosis is required for C

Elizabeth J English, Sarah A Mahn, Adriano Marchese

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 50 citations in OpenAlex.

  1. Oncogenic Gα signaling requires AP-3-dependent recruitment to the endolysosomal compartment.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  18. Wnt/β-Catenin Signaling Regulates CXCR4 Expression and [Diagnostics (Basel, Switzerland) · 2021
    Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Elizabeth J EnglishDepartment of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin 53226.
Sarah A MahnDepartment of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin 53226.
Adriano MarcheseDepartment of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin 53226. Electronic address: amarchese@mcw.edu.
Medical College of Wisconsin · US

Funding

Role of beta-arrestins in G protein-coupled receptor sorting and signalingR01GM106727 · NIGMS · MEDICAL COLLEGE OF WISCONSIN · PI MARCHESE, ADRIANO · 2014 to 2022
$2.9M
GPCR regulation of Akt signalingR01GM122889 · NIGMS · MEDICAL COLLEGE OF WISCONSIN · PI MARCHESE, ADRIANO · 2017 to 2020
$1.3M
NIGMS NIH HHS R01 GM106727NIGMS NIH HHS R01 GM122889
6 · The paper itself

Abstract

Signaling activated by binding of the C

Indexed as

ApoptosisEndocytosisSignal TransductionExtracellular Signal-Regulated MAP KinasesHeLa CellsHumansMAP Kinase Signaling SystemPhosphorylationProto-Oncogene Proteins c-aktReceptors, CXCR4Extracellular Signal-Regulated MAP KinasesProto-Oncogene Proteins c-aktReceptors, CXCR4Akt PKBanoikisapoptosischemokineC-X-C chemokine receptor type 4 (CXCR-4)endocytosisendosomeFOXOG protein-coupled receptor (GPCR)

Identifiers

PMID29899118
PMCPMC6065176
OpenAlexW2807857147

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.