Evidence map›Paper›PMID 29899113›Full record

ArticleThe Journal of biological chemistry2018

Tribbles homolog 1 deficiency modulates function and polarization of murine bone marrow-derived macrophages.

Lilli Arndt, Janine Dokas, Martin Gericke, Carl Elias Kutzner, Silvana Müller, Franziska Jeromin, Joachim Thiery, Ralph Burkhardt

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
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  10. Review
  11. Effect ofFrontiers in immunology · 2022
    Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Trouble With Tribbles-1.Arteriosclerosis, thrombosis, and vascular biology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Lilli ArndtInstitute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, 04103 Leipzig, Germany.
Janine DokasInstitute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, 04103 Leipzig, Germany.
Martin GerickeInstitute of Anatomy, University of Leipzig, 04103 Leipzig, Germany.
Carl Elias KutznerInstitute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, 04103 Leipzig, Germany.
Silvana MüllerInstitute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, 04103 Leipzig, Germany.
Franziska JerominInstitute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, 04103 Leipzig, Germany.
Joachim ThieryInstitute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, 04103 Leipzig, Germany; LIFE-Leipzig Research Center for Civilization Diseases, University of Leipzig, 04103 Leipzig, Germany.
Ralph BurkhardtInstitute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, 04103 Leipzig, Germany; LIFE-Leipzig Research Center for Civilization Diseases, University of Leipzig, 04103 Leipzig, Germany. Electronic address: ralph.burkhardt@medizin.uni-leipzig.de.
University Hospital Leipzig · DELeipzig University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macrophages are essential for innate immunity and inflammatory responses and differentiate into various functional phenotypes. Tribbles homolog 1 (

Indexed as

Cell MovementCell PolarityGene DeletionPhagocytosisAnimalsBone Marrow CellsIntracellular Signaling Peptides and ProteinsJanus Kinase 1MacrophagesMaleMiceMice, Inbred C57BLProtein Serine-Threonine KinasesSignal TransductionSTAT Transcription FactorsIntracellular Signaling Peptides and ProteinsJanus Kinase 1Protein Serine-Threonine KinasesSTAT Transcription FactorsTrib1 protein, mouseJanus kinase (JAK)M1/M2macrophagemigrationphagocytosispolarizationsignal transductionSTAT transcription factor

Identifiers

PMID29899113
PMCPMC6065162
OpenAlexW2808678463

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.