Evidence map›Paper›PMID 29899089›Full record

ReviewJournal of virology2018

Role of Microtubules and Microtubule-Associated Proteins in HIV-1 Infection.

Adarsh Dharan, Edward M Campbell

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Retroviruses use different IPNature communications · 2026
    Article
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  14. Review
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  18. Article
  19. Virus-Induced Membrane Fusion in Neurodegenerative Disorders.Frontiers in cellular and infection microbiology · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Adarsh DharanDepartment of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, USA.
Edward M CampbellDepartment of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, USA ecampbell@luc.edu.
Loyola University Chicago · US

Funding

Role of Cellular Factors in Retroviral Uncoating and Synthesis of Viral DNAR01AI087390 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI DIAZ-GRIFFERO, FELIPE · 2010 to 2024
$6.8M
Defining the microtubule motors which drive the uncoating and trafficking of HIVR01AI120956 · NIAID · LOYOLA UNIVERSITY CHICAGO · PI CAMPBELL, EDWARD M, DIAZ-GRIFFERO, FELIPE · 2015 to 2019
$1.6M
Exploring the role of microtubules in HIV-1 uncoatingR21AI106547 · NIAID · LOYOLA UNIVERSITY CHICAGO · PI CAMPBELL, EDWARD M · 2013 to 2014
$390k
NIAID NIH HHS R01 AI120956NIAID NIH HHS R21 AI106547
6 · The paper itself

Abstract

Recent studies show that human immunodeficiency virus type 1 (HIV-1) can utilize microtubules and their associated proteins to complete key postfusion steps during infection. These include associating with both dynein and kinesin motors, as well as proteins, which enhance infection by altering microtubule dynamics during infection. In this article, we will discuss findings on how dynein and kinesin motors, as well as other microtubule-associated proteins, influence HIV-1 trafficking, viral core uncoating, and nuclear import of the viral ribonucleoprotein (RNP).

Indexed as

Host-Pathogen InteractionsActive Transport, Cell NucleusHIV-1HIV InfectionsHumansMicrotubule-Associated ProteinsMicrotubulesViral ProteinsVirus UncoatingMicrotubule-Associated ProteinsViral ProteinsBICD2dyneinEB1FEZ1HIV-1kinesin-1microtubules

Identifiers

PMID29899089
PMCPMC6069196
OpenAlexW2806841950

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.