ArticleCirculation. Genomic and precision medicine2018
Open access · bronzeAbstract read
In one paragraph
Article in Circulation. Genomic and precision medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 12% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Pooled it
- Pooled it
- Update on APOL1 and chronic kidney diseases in children.Pediatric nephrology (Berlin, Germany) · 2026Review
- Trends and disparities in heart failure mortality with and without chronic kidney disease in a nationwide retrospective analysis.Scientific reports · 2025Article
- G1 and G2 ApolipoproteinL1 modulate macrophage inflammation and lipid accumulation through the polyamine pathway.bioRxiv : the preprint server for biology · 2025Article
- Apolipoprotein-L1 G1 variant contributes to hydrocephalus but not to atherosclerosis in apolipoprotein-E knock-out mice.Clinical science (London, England : 1979) · 2025Article
- Article
- Article
- Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease.Nature communications · 2023Article
- The metabolic effects of APOL1 in humans.Pflugers Archiv : European journal of physiology · 2023Review
- Health inequities and the inappropriate use of race in nephrology.Nature reviews. Nephrology · 2022Review
- Article
- APOL1 Risk Variants Associated with Serum Albumin in a Population-Based Cohort Study.American journal of nephrology · 2022Article
- APOL1 G3 Variant Is Associated with Cardiovascular Mortality and Sudden Cardiac Death in Patients Receiving Maintenance Hemodialysis of European Ancestry.Cardiorenal medicine · 2022Article
- Article
- Stroke in Africa: profile, progress, prospects and priorities.Nature reviews. Neurology · 2021Review
- Article
- Apolipoprotein L1 risk genotypes in Ghanaian patients with systemic lupus erythematosus: a prospective cohort study.Lupus science & medicine · 2021Article
- Association ofCirculation · 2019Article
- Apolipoprotein L1, Cardiovascular Disease and Hypertension: More Questions than Answers.Cardiology clinics · 2019Review
Corrections and comments
- Commented on by
Authors and funding
16 authors at 11 institutions in 2 countries.
Orlando M GutiérrezDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL (O.M.G.).
Marguerite R IrvinDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL (M.R.I., N.S.C.).
Ninad S ChaudharyDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL (M.R.I., N.S.C.).
Mary CushmanDivision of Hematology and Oncology, University of Vermont, Burlington, VT (M.C., N.A.Z.).
Neil A ZakaiDivision of Hematology and Oncology, University of Vermont, Burlington, VT (M.C., N.A.Z.).
Victor A DavidBasic Research Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD (V.A.D.).
Sophie LimouBasic Research Laboratory, National Cancer Institute, National Institutes of Health, Leidos Biomedical Research, Frederick National Laboratory, Frederick, MD (S.L., C.A.W.).
Nathalie PamirKnight Cardiovascular Institute, Oregon Health and Science University, Portland, OR (N.P.).
Alex P ReinerDepartment of Epidemiology, University of Washington, Seattle, WA (A.P.R.).
Rakhi P NaikDepartment of Medicine, Johns Hopkins School of Medicine, Johns Hopkins University, Baltimore, MD (R.P.N.).
Michele M SaleCenter for Public Health Genomics, University of Virginia, Charlottesville, VA (M.M. Sale).
Monika M SaffordDivision of General Internal Medicine, Weill Cornell Medicine, New York, NY (M.M. Safford).
Hyacinth I HyacinthDepartment of Pediatrics, Aflac Cancer and Blood Disorder Center, Children's Healthcare of Atlanta, Emory University, Atlanta, GA (H.I.H.).
Suzanne E JuddDepartment of Biostatistics, University of Alabama at Birmingham, Birmingham, AL (S.E.J.).
Jeffrey B KoppKidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD (J.B.K.). winklerc@mail.nih.gov jeffreyk@intra.niddk.nih.gov.
Cheryl A WinklerBasic Research Laboratory, National Cancer Institute, National Institutes of Health, Leidos Biomedical Research, Frederick National Laboratory, Frederick, MD (S.L., C.A.W.) winklerc@mail.nih.gov jeffreyk@intra.niddk.nih.gov.
University of Alabama at Birmingham · USUniversity of Vermont · USEmory University · USFrederick National Laboratory for Cancer Research · USJohns Hopkins University · USLeidos Biomedical Research Inc. (United States)Nantes Université · FROregon Health & Science University · USUniversity of Virginia · USUniversity of Washington · USWeill Cornell Medicine · US
Funding
VCID and Stroke in a Bi-racial National CohortU01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CUSHMAN, MARY, HOWARD, GEORGE · 2002 to 2022
$96.0MUniversity of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5MFocal Segmental Glomerulosclerosis: Genetics & MechanismsZIADK043308 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI KOPP, JEFFREY BURNETT · 2009 to 2024
$15.7MGenetics of Renal Disease in African AmericansZIABC010022 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WINKLER, CHERYL · 2009 to 2022
$8.9MUnderstanding Cohort Effects on Stroke, VCID, and Cognition After Major Epidemiologic TransitionsR01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MARY CUSHMAN, VIRGINIA J. HOWARD · 2001 to 2026
$8.8MMechanism of cerebral vaculopathy and stroke in sickle cell diseaseR01HL138423 · NHLBI · UNIVERSITY OF CINCINNATI · PI HYACINTH, HYACINTH IDU · 2017 to 2021
$2.5MIdentification of the role of HDL function in human cardiovascular disease through proteomics and geneticsR01HL136373 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI PAMIR, NATHALIE · 2018 to 2022
$2.4MBeyond the Glomerulus: Novel Clinical Markers of Kidney Health and PrognosisU01DK102730 · NIDDK · TUFTS MEDICAL CENTER · PI GUTIERREZ, ORLANDO M, IX, JOACHIM H · 2016 to 2020
$1.9MImpact of disordered mineral metabolism on stroke and cognitive impairmentR01NS080850 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GUTIERREZ, ORLANDO M · 2012 to 2016
$1.2MNCI NIH HHS HHSN261200800001ENHLBI NIH HHS R01 HL136373NHLBI NIH HHS R01 HL138423NIDDK NIH HHS P30 DK079626NIDDK NIH HHS U01 DK102730NIMHD NIH HHS L60 MD013112NINDS NIH HHS R01 NS041588NINDS NIH HHS R01 NS080850NINDS NIH HHS U01 NS041588
Abstract
background
methodsWe examined associations of
results
conclusions
Indexed as
MutationAdultApolipoprotein L1Black or African AmericanCardiovascular DiseasesFemaleGenotypeHumansIncidenceMaleMiddle AgedRenal Insufficiency, ChronicRisk FactorsUnited StatesWhite PeopleAPOL1 protein, humanApolipoprotein L1cardiac catheterizationcardiovascular diseasesgeneticsmyocardial infarctionstroke
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.