ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018
Comparison of Decision-Related Signals in Sensory and Motor Preparatory Responses of Neurons in Area LIP.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Decoupling Choice from Motor Response Reduces Choice-History Effects.bioRxiv : the preprint server for biology · 2026Article
- Sensorimotor transformation of number in the primate parietal cortex.Nature communications · 2026Article
- Nonlinear feedback modulation contributes to the optimization of flexible decision-making.eLife · 2025Article
- Neural basis of concurrent deliberation toward a choice and confidence judgment.bioRxiv : the preprint server for biology · 2025Article
- Article
- Differential clustering of visual and choice- and saccade-related activity in macaque V3A and CIP.Journal of neurophysiology · 2024Article
- Transient Oscillations of Neural Firing Rate Associated With Routing of Evidence in a Perceptual Decision.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Sequential sampling from memory underlies action selection during abstract decision-making.Current biology : CB · 2022Article
- Perceptual decisions and oculomotor responses rely on temporally distinct streams of evidence.Communications biology · 2022Article
- Altered microstructural properties of superficial white matter in patients with Parkinson's disease.Brain imaging and behavior · 2022Article
- Article
- Stimulus-dependent relationships between behavioral choice and sensory neural responses.eLife · 2021Article
- Neural Substrates of the Drift-Diffusion Model in Brain Disorders.Frontiers in computational neuroscience · 2021Review
- Article
- The functional roles of neural remapping in cortex.Journal of vision · 2020Article
- Evidence accumulation during perceptual decisions in humans varies as a function of dorsal frontoparietal organization.Nature human behaviour · 2020Article
- Fast and reversible neural inactivation in macaque cortex by optogenetic stimulation of GABAergic neurons.eLife · 2020Article
- Differentiating between integration and non-integration strategies in perceptual decision making.eLife · 2020Article
- Discovering Precise Temporal Patterns in Large-Scale Neural Recordings through Robust and Interpretable Time Warping.Neuron · 2020Article
- Learning, memory and consolidation mechanisms for behavioral control in hierarchically organized cortico-basal ganglia systems.Hippocampus · 2020Review
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3 authors.
Funding
Abstract
Neurons in the lateral intraparietal (LIP) area of Macaques exhibit both sensory and oculomotor preparatory responses. During perceptual decision making, the preparatory responses have been shown to track the state of the evolving evidence leading to the decision. The sensory responses are known to reflect categorical properties of visual stimuli, but it is not known whether these responses also track evolving evidence. We recorded neural responses from lateral intraparietal area of 2 female rhesus monkeys during a direction discrimination task. We compared sensory and oculomotor-preparatory responses in the same neurons when either the discriminandum (random dot motion) or an eye movement choice-target was in the neuron's response field. The neural responses in both configurations reflected the strength and direction of motion and were correlated with the animal's choice, albeit more prominently when the choice-target was in the response field. However, the variance and autocorrelation pattern of only the motor preparatory responses reflected the process of evidence accumulation. Simulations suggest that the task related activity of sensory responses could be inherited through lateral interactions with neurons that are carrying evidence accumulation signals in their motor-preparatory responses. The results are consistent with the proposal that evolving decision processes are supported by persistent neural activity in the service of actions or intentions, as opposed to high-order representations of stimulus properties.
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